Christina M Pinkston1, Richard N Baumgartner2, Avonne E Connor1, Stephanie D Boone2, Kathy B Baumgartner3. 1. Department of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, USA. 2. Department of Epidemiology and Population Health, School of Public Health and Information Sciences, James Graham Brown Cancer Center, University of Louisville, 485 E. Gray St., Louisville, 40202, KY, USA. 3. Department of Epidemiology and Population Health, School of Public Health and Information Sciences, James Graham Brown Cancer Center, University of Louisville, 485 E. Gray St., Louisville, 40202, KY, USA. kbbaum01@louisville.edu.
Abstract
PURPOSE: We investigated the association of physical activity with survival for 601 Hispanic women and 682 non-Hispanic white women who participated in the population-based breast cancer case-control New Mexico Women's Health Study. METHODS: We identified 240 deaths among cases diagnosed with a first primary invasive breast cancer between 1992 and 1994, and 88 deaths among controls. Follow-up extended through 2012 for cases and 2008 for controls. Multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards regression. RESULTS: Higher levels of total physical activity were inversely associated with all-cause mortality among Hispanic cases (Quartile (Q)4: HR = 0.55, 95% CI 0.31-0.99). A non-significant trend was observed for recreational activity in Hispanic cases also (Q4: HR = 0.50, 95% CI 0.23-1.09, p for trend = 0.08). No significant associations were noted for non-Hispanic white cases or for controls. CONCLUSIONS: The results suggest that increasing physical activity may be protective against mortality in Hispanic women with breast cancer, despite reporting lower levels of recreational activity than non-Hispanic white women or Hispanic controls. IMPLICATIONS FOR CANCER SURVIVORS: Public health programs in Hispanic communities should promote physical activity in women as a means of decreasing breast cancer risk and improving survival.
PURPOSE: We investigated the association of physical activity with survival for 601 Hispanic women and 682 non-Hispanic white women who participated in the population-based breast cancer case-control New Mexico Women's Health Study. METHODS: We identified 240 deaths among cases diagnosed with a first primary invasive breast cancer between 1992 and 1994, and 88 deaths among controls. Follow-up extended through 2012 for cases and 2008 for controls. Multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards regression. RESULTS: Higher levels of total physical activity were inversely associated with all-cause mortality among Hispanic cases (Quartile (Q)4: HR = 0.55, 95% CI 0.31-0.99). A non-significant trend was observed for recreational activity in Hispanic cases also (Q4: HR = 0.50, 95% CI 0.23-1.09, p for trend = 0.08). No significant associations were noted for non-Hispanic white cases or for controls. CONCLUSIONS: The results suggest that increasing physical activity may be protective against mortality in Hispanic women with breast cancer, despite reporting lower levels of recreational activity than non-Hispanic white women or Hispanic controls. IMPLICATIONS FOR CANCER SURVIVORS: Public health programs in Hispanic communities should promote physical activity in women as a means of decreasing breast cancer risk and improving survival.
Entities:
Keywords:
Breast cancer survivor; Hispanic; Mortality; Physical activity; Survival analysis
Authors: Tim Byers; Marion Nestle; Anne McTiernan; Colleen Doyle; Alexis Currie-Williams; Ted Gansler; Michael Thun Journal: CA Cancer J Clin Date: 2002 Mar-Apr Impact factor: 508.702
Authors: Page E Abrahamson; Marilie D Gammon; Mary Jo Lund; Julie A Britton; Stephen W Marshall; Elaine W Flagg; Peggy L Porter; Louise A Brinton; J William Eley; Ralph J Coates Journal: Cancer Date: 2006-10-15 Impact factor: 6.860
Authors: Patrick T Bradshaw; Joseph G Ibrahim; Nikhil Khankari; Rebecca J Cleveland; Page E Abrahamson; June Stevens; Jessie A Satia; Susan L Teitelbaum; Alfred I Neugut; Marilie D Gammon Journal: Breast Cancer Res Treat Date: 2014-05-01 Impact factor: 4.872
Authors: K B Baumgartner; W C Hunt; R N Baumgartner; D D Crumley; F D Gilliland; A McTiernan; L Bernstein; R Ballard-Barbash Journal: Am J Epidemiol Date: 2004-12-01 Impact factor: 4.897
Authors: Barbara Sternfeld; Erin Weltzien; Charles P Quesenberry; Adrienne L Castillo; Marilyn Kwan; Martha L Slattery; Bette J Caan Journal: Cancer Epidemiol Biomarkers Prev Date: 2009-01 Impact factor: 4.254
Authors: Caitlin Mason; Catherine M Alfano; Ashley Wilder Smith; Ching-Yun Wang; Marian L Neuhouser; Catherine Duggan; Leslie Bernstein; Kathy B Baumgartner; Richard N Baumgartner; Rachel Ballard-Barbash; Anne McTiernan Journal: Cancer Epidemiol Biomarkers Prev Date: 2013-04-10 Impact factor: 4.254
Authors: R E Frisch; G Wyshak; N L Albright; T E Albright; I Schiff; K P Jones; J Witschi; E Shiang; E Koff; M Marguglio Journal: Br J Cancer Date: 1985-12 Impact factor: 7.640
Authors: Richard N Baumgartner; Avonne E Connor; Yunfeng Cao; Kathy B Baumgartner; Kala Visvanathan; Stephanie D Boone Journal: NPJ Breast Cancer Date: 2020-10-09
Authors: Kate E Dibble; Richard N Baumgartner; Stephanie D Boone; Kathy B Baumgartner; Avonne E Connor Journal: Breast Cancer Res Treat Date: 2021-05-29 Impact factor: 4.624