Daniel López-López1, Carlos Agrasar-Cruz2, Adolfo Bautista-Casasnovas3, Carlos Javier Álvarez-Castro1. 1. Departamento de Ciencias de la Salud, Facultad de Enfermería y Podología, Universidade da Coruña, España. 2. Departamento de Medicina, Facultad de Ciencias de la Salud, Universidade da Coruña, España. 3. Departamento de Pediatría, Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, España.
Abstract
INTRODUCTION: Plantar warts often are refractory to any treatment and can last for decades in adults. Recalcitrant warts are defined as those that have persisted for more than two years, or after at least two treatment modalities. METHODS: A total of 15 consecutive patients with recalcitrant plantar warts were included in this preliminary study. The treatment consisted of applying one to two sessions that comprised compounding 1% cantharidin, 5% of podophyllotoxin, and 30% salicylic acid (CPS), with an interval between applications of four weeks. RESULTS: With treatment and subsequent follow-up for six months, there was complete eradication of lesions in 15 patients, eight (53.3%) required a single application of the solution, and seven (46.7%) two applications, with no side effects. Patient satisfaction related to treatment was measured by a visual analog scale (VAS) of 10 cm in length, with an average score 9.73 ± 0.46, and all said they would proceed with the treatment again if necessary. CONCLUSIONS: Topical treatment by compounding is safe, effective, and a promising therapeutic modality when applied in recalcitrant plantar warts.
INTRODUCTION: Plantar warts often are refractory to any treatment and can last for decades in adults. Recalcitrant warts are defined as those that have persisted for more than two years, or after at least two treatment modalities. METHODS: A total of 15 consecutive patients with recalcitrant plantar warts were included in this preliminary study. The treatment consisted of applying one to two sessions that comprised compounding 1% cantharidin, 5% of podophyllotoxin, and 30% salicylic acid (CPS), with an interval between applications of four weeks. RESULTS: With treatment and subsequent follow-up for six months, there was complete eradication of lesions in 15 patients, eight (53.3%) required a single application of the solution, and seven (46.7%) two applications, with no side effects. Patient satisfaction related to treatment was measured by a visual analog scale (VAS) of 10 cm in length, with an average score 9.73 ± 0.46, and all said they would proceed with the treatment again if necessary. CONCLUSIONS: Topical treatment by compounding is safe, effective, and a promising therapeutic modality when applied in recalcitrant plantar warts.
Authors: Anh Ly Nguyen; Koen D Quint; Jan Nico Bouwes Bavinck; Angelina Erceg; Wim J A de Kort; John E M Körver Journal: Dermatol Ther Date: 2019-11-20 Impact factor: 2.851
Authors: Scott Guenthner; Wendy McFalda; Pearl Kwong; Kimberly Eads; Morgan McCafferty; Jayson Rieger; David K Glover; Cynthia Willson; Patrick Burnett; Melissa Olivadoti Journal: Dermatol Ther (Heidelb) Date: 2021-07-21