Literature DB >> 25739303

[Effect of embryonic anlage allografts of the rat spinal cord on growth of regenerating fibers of the recipient nerve].

E S Petrova, E N Isaeva.   

Abstract

A comparative study of the effect of tissue and suspension allografts of an embryonic spinal cord on regeneration of nerve fibers of impaired (by application of a ligature) sciatic nerve in rats was conducted. It was demonstrated that unlike tissue grafts that reach a large volume 21 and 60 days after transplantation, suspension grafts do not inhibit the growth of axons of the recipient to the periphery. It was established that introduction of a suspension of dissociated cells of the spinal cord embryonic anlages (but not fragments of these anlages) into the impaired sciatic nerve in rats results in an increase in the amount of myelinated regenerating nerve fibers of the recipient 60 days after the operation.

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Year:  2014        PMID: 25739303

Source DB:  PubMed          Journal:  Izv Akad Nauk Ser Biol        ISSN: 1026-3470


  2 in total

1.  Injured Nerve Regeneration using Cell-Based Therapies: Current Challenges.

Authors:  E S Petrova
Journal:  Acta Naturae       Date:  2015 Jul-Sep       Impact factor: 1.845

2.  Regenerative Effects and Development Patterns of Solid Neural Tissue Grafts Located in Gelatin Hydrogel Conduit for Treatment of Peripheral Nerve Injury.

Authors:  Kirill K Sukhinich; Erdem B Dashinimaev; Ekaterina A Vorotelyak; Maria A Aleksandrova
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-02-11
  2 in total

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