Literature DB >> 25738512

Site-specific chemical modification of peptide and protein by thiazolidinediones.

Peng Wang, Shumei Zhang, Qiuyue Meng, Ying Liu, Luqing Shang, Zheng Yin.   

Abstract

A direct aldol reaction employing 2,4-thiazolidinediones as nucleophilic donors was performed to modify peptides and protein under mild conditions. Various functional groups could be readily introduced into protein without conformation change.

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Year:  2015        PMID: 25738512     DOI: 10.1021/acs.orglett.5b00005

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Amino-Acid-Catalyzed Direct Aldol Bioconjugation.

Authors:  Tiauna S Howard; Ryan D Cohen; Ogonna Nwajiobi; Zilma P Muneeswaran; Yonnette E Sim; Neelam N Lahankar; Johannes T-H Yeh; Monika Raj
Journal:  Org Lett       Date:  2018-08-20       Impact factor: 6.005

2.  An expeditious route to sterically encumbered nonproteinogenic α-amino acid precursors using allylboronic acids.

Authors:  Samrat Sahu; Ganesh Karan; Lisa Roy; Modhu Sudan Maji
Journal:  Chem Sci       Date:  2022-01-28       Impact factor: 9.825

3.  Bifunctional Reagents for Formylglycine Conjugation: Pitfalls and Breakthroughs.

Authors:  Nils Janson; Tobias Krüger; Lennard Karsten; Mareile Boschanski; Thomas Dierks; Kristian M Müller; Norbert Sewald
Journal:  Chembiochem       Date:  2020-09-18       Impact factor: 3.164

  3 in total

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