AIMS: The use of natural plant extracts in pharmacology, medicine and dental hygiene has found a growing interest in modern scientific research. Salvadora persica is a natural tree whose fibrous branches have been approved by the World Health Organization for oral hygiene. Periodontitis is a highly prevalent adult gingival disease that leads to bone destruction and connective tissue attachment loss. The aim of this research was assessment the antimicrobial activities of methanolic extract of Salvadora persica (miswak) on isolated strains from the oral fluid. METHODS: In practical section, 50 female university students (21.4 ± 1 year) participated in the study. Based on examination by a periodontist, they were grouped into (Group I, n = 21) and (Group II, n = 29) i.e. with and without periodontitis respectively. Their un-stimulated saliva samples were obtained in sterile tubes. While three bacterial genera, Staphylococcus, Streptococcus and Lactobacillus were identified in all subjects, Enterococcus and Escherichia were only detected in Group I. RESULTS: A statistically significant difference in colonization levels between the two groups was observed. The effect of methanolic extract of S. persica against oral bacterial strains isolated from saliva was investigated using agar disc diffusion and microdilution methods. Although methanolic extract of S. persica was effective on growth inhibition of all strains, it was significantly more effective on Gram positive bacteria than Gram negative ones. CONCLUSIONS: Effective substances present in S. persica extracts, exhibit a broad range of antibacterial activity and affect almost all bacterial species regardless of the Gram-staining nature.
AIMS: The use of natural plant extracts in pharmacology, medicine and dental hygiene has found a growing interest in modern scientific research. Salvadora persica is a natural tree whose fibrous branches have been approved by the World Health Organization for oral hygiene. Periodontitis is a highly prevalent adult gingival disease that leads to bone destruction and connective tissue attachment loss. The aim of this research was assessment the antimicrobial activities of methanolic extract of Salvadora persica (miswak) on isolated strains from the oral fluid. METHODS: In practical section, 50 female university students (21.4 ± 1 year) participated in the study. Based on examination by a periodontist, they were grouped into (Group I, n = 21) and (Group II, n = 29) i.e. with and without periodontitis respectively. Their un-stimulated saliva samples were obtained in sterile tubes. While three bacterial genera, Staphylococcus, Streptococcus and Lactobacillus were identified in all subjects, Enterococcus and Escherichia were only detected in Group I. RESULTS: A statistically significant difference in colonization levels between the two groups was observed. The effect of methanolic extract of S. persica against oral bacterial strains isolated from saliva was investigated using agar disc diffusion and microdilution methods. Although methanolic extract of S. persica was effective on growth inhibition of all strains, it was significantly more effective on Gram positive bacteria than Gram negative ones. CONCLUSIONS: Effective substances present in S. persica extracts, exhibit a broad range of antibacterial activity and affect almost all bacterial species regardless of the Gram-staining nature.
Authors: Mohammed A El-Bali; Abdulhafid Abdulhakim; Raafat T Mohamed; Mohamed A El-Malky; Rowaida A Bakri; Saeed A Al-Harthi Journal: J Parasit Dis Date: 2020-07-27
Authors: Paulo Henrique Utumi; Letícia Fracaro; Felipe Yukio Ishikawa Fragoso; Dayane Mayumi Miyasaki; Paula Joly Dos Santos; Lidiane Maria Boldrini-Leite; Paulo Roberto Slud Brofman; José Ademar Villanova; Alexandra Cristina Senegaglia Journal: J Oral Biol Craniofac Res Date: 2020-07-03
Authors: Mohamed Saeed Zayed Al-Ayed; Ahmed Morad Asaad; Mohamed Ansar Qureshi; Hany Goda Attia; Abduljabbar Hadi AlMarrani Journal: Evid Based Complement Alternat Med Date: 2016-01-19 Impact factor: 2.629
Authors: Shahabe Abullais Saquib; Nabeeh Abdullah AlQahtani; Irfan Ahmad; Mohammed Abdul Kader; Sami Saeed Al Shahrani; Elyas Ali Asiri Journal: Antibiotics (Basel) Date: 2019-07-01