Literature DB >> 25737584

Integrating p38α MAPK immune signals in nonimmune cells.

Sarah L Gaffen1, Mandy J McGeachy2.   

Abstract

A study by Huang et al. in this issue of Science Signaling highlights key roles for the mitogen-activated protein kinase p38α and the phosphatase MK1 in mediating interleukin-17-dependent pathology in experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis.
Copyright © 2015, American Association for the Advancement of Science.

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Year:  2015        PMID： 25737584      PMCID： PMC4805373          DOI： 10.1126/scisignal.aaa8398

Source DB:  PubMed          Journal:  Sci Signal        ISSN： 1945-0877            Impact factor:   8.192


  11 in total

1.  The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

Authors:  Mohamed El-Behi; Bogoljub Ciric; Hong Dai; Yaping Yan; Melissa Cullimore; Farinaz Safavi; Guang-Xian Zhang; Bonnie N Dittel; Abdolmohamad Rostami
Journal:  Nat Immunol       Date:  2011-04-24       Impact factor: 25.606

2.  RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

Authors:  Laura Codarri; Gabor Gyülvészi; Vinko Tosevski; Lysann Hesske; Adriano Fontana; Laurent Magnenat; Tobias Suter; Burkhard Becher
Journal:  Nat Immunol       Date:  2011-04-24       Impact factor: 25.606

3.  Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.

Authors:  Zizhen Kang; Chenhui Wang; Jarod Zepp; Ling Wu; Kevin Sun; Junjie Zhao; Unni Chandrasekharan; Paul E DiCorleto; Bruce D Trapp; Richard M Ransohoff; Xiaoxia Li
Journal:  Nat Neurosci       Date:  2013-09-01       Impact factor: 24.884

Review 4.  Functional specialization of interleukin-17 family members.

Authors:  Yoichiro Iwakura; Harumichi Ishigame; Shinobu Saijo; Susumu Nakae
Journal:  Immunity       Date:  2011-02-25       Impact factor: 31.745

Review 5.  The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing.

Authors:  Sarah L Gaffen; Renu Jain; Abhishek V Garg; Daniel J Cua
Journal:  Nat Rev Immunol       Date:  2014-09       Impact factor: 53.106

Review 6.  Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease.

Authors:  Reiko M Onishi; Sarah L Gaffen
Journal:  Immunology       Date:  2010-03       Impact factor: 7.397

7.  Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis.

Authors:  Zizhen Kang; Cengiz Zubeyir Altuntas; Muhammet Fatih Gulen; Caini Liu; Natalia Giltiay; Hongwei Qin; Liping Liu; Wen Qian; Richard M Ransohoff; Cornelia Bergmann; Stephen Stohlman; Vincent K Tuohy; Xiaoxia Li
Journal:  Immunity       Date:  2010-03-18       Impact factor: 31.745

8.  IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence.

Authors:  Shyamasree Datta; Michael Novotny; Paul G Pavicic; Chenyang Zhao; Tomasz Herjan; Justin Hartupee; Thomas Hamilton
Journal:  J Immunol       Date:  2009-12-30       Impact factor: 5.422

Review 9.  Mitogen-activated protein kinases in innate immunity.

Authors:  J Simon C Arthur; Steven C Ley
Journal:  Nat Rev Immunol       Date:  2013-08-19       Impact factor: 53.106

10.  Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation.

Authors:  Gonghua Huang; Yanyan Wang; Peter Vogel; Thirumala-Devi Kanneganti; Kinya Otsu; Hongbo Chi
Journal:  Nat Immunol       Date:  2012-01-08       Impact factor: 25.606
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  3 in total

1.  [Interleukin-17 promotes mouse hepatoma cell proliferation by antagonizing interferon-γ].

Authors:  Jie Li; Kun Yan; Yi Yang; Hua Li; Zhidong Wang; Xin Xu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2019-01-30

2.  IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells.

Authors:  Jing-kun Li; Lin Nie; Yun-peng Zhao; Yuan-qiang Zhang; Xiaoqing Wang; Shuai-shuai Wang; Yi Liu; Hua Zhao; Lei Cheng
Journal:  J Transl Med       Date:  2016-03-17       Impact factor: 5.531

3.  LION LBD: a literature-based discovery system for cancer biology.

Authors:  Sampo Pyysalo; Simon Baker; Imran Ali; Stefan Haselwimmer; Tejas Shah; Andrew Young; Yufan Guo; Johan Högberg; Ulla Stenius; Masashi Narita; Anna Korhonen
Journal:  Bioinformatics       Date:  2019-05-01       Impact factor: 6.937
  3 in total

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