Yuag-Meng Liu1, Yi-Tzu Lee2, Shu-Chen Kuo3, Te-Li Chen4, Chang-Pan Liu5, Chun-Eng Liu6. 1. Division of Infectious Diseases, Changhua Christian Hospital, Changhua, Taiwan. 2. Institutes of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Emergency Department, Taipei Veterans General Hospital, Taipei, Taiwan. 3. Institutes of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan; Division of Infectious Diseases, Taipei Veterans General Hospital, Taipei, Taiwan. 4. Institutes of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Infectious Diseases, Taipei Veterans General Hospital, Taipei, Taiwan; Division of Infectious Diseases, Cheng Hsin General Hospital, Taipei, Taiwan. 5. Division of Infectious Diseases, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan. Electronic address: joeliu5929@hotmail.com.tw. 6. Division of Infectious Diseases, Changhua Christian Hospital, Changhua, Taiwan. Electronic address: 63557@cch.org.tw.
Abstract
BACKGROUND/ PURPOSE: Patients with Acinetobacter pittii and Acinetobacter nosocomialis bacteremia have lower mortality rates than those with Acinetobacter baumannii bacteremia. However, it is unknown whether these organisms differ in outcomes of bacteremic patients. We conducted this study to answer this question. METHODS: In this retrospective study conducted at a teaching hospital in Taiwan, we enrolled all 86 patients who had developed A. pittii bacteremia and those with A. nosocomialis bacteremia from 2000 to 2008 while matching for age, sex, Acute Physiology and Chronic Health Evaluation II score, and appropriate antimicrobial therapy. After adjustment, we accessed the clinical characteristics and 14- and 28-day mortalities. RESULTS: We found that the patients with A. pittii bacteremia had multiple comorbidities less often and received invasive procedures less frequently. The 14-day mortality rate of patients with A. pittii or A. nosocomialis bacteremia was 14% and 7%, respectively, whereas their 28-day mortality rate was 17% and 9%, respectively. Using the mortality rate in patients with A. nosocomialis bacteremia as a reference, the odds ratios for the 14- and 28-day crude morality in those with A. pittii were 2.16 [95% confidence interval (CI), 0.77-6.05] and 2.06 (95% CI, 0.82-5.15), respectively, whereas the adjusted odds ratios for 14- and 28-day mortality were 1.89 (95% CI, 0.56-6.14) and 1.67 (95% CI, 0.59-4.78) respectively. CONCLUSION: Our 8-year study showed that the mortality rate of A. pittii bacteremia was higher but the difference was not statistically significant.
BACKGROUND/ PURPOSE:Patients with Acinetobacter pittii and Acinetobacter nosocomialis bacteremia have lower mortality rates than those with Acinetobacter baumannii bacteremia. However, it is unknown whether these organisms differ in outcomes of bacteremic patients. We conducted this study to answer this question. METHODS: In this retrospective study conducted at a teaching hospital in Taiwan, we enrolled all 86 patients who had developed A. pittii bacteremia and those with A. nosocomialis bacteremia from 2000 to 2008 while matching for age, sex, Acute Physiology and Chronic Health Evaluation II score, and appropriate antimicrobial therapy. After adjustment, we accessed the clinical characteristics and 14- and 28-day mortalities. RESULTS: We found that the patients with A. pittii bacteremia had multiple comorbidities less often and received invasive procedures less frequently. The 14-day mortality rate of patients with A. pittii or A. nosocomialis bacteremia was 14% and 7%, respectively, whereas their 28-day mortality rate was 17% and 9%, respectively. Using the mortality rate in patients with A. nosocomialis bacteremia as a reference, the odds ratios for the 14- and 28-day crude morality in those with A. pittii were 2.16 [95% confidence interval (CI), 0.77-6.05] and 2.06 (95% CI, 0.82-5.15), respectively, whereas the adjusted odds ratios for 14- and 28-day mortality were 1.89 (95% CI, 0.56-6.14) and 1.67 (95% CI, 0.59-4.78) respectively. CONCLUSION: Our 8-year study showed that the mortality rate of A. pittii bacteremia was higher but the difference was not statistically significant.
Authors: Tark Kim; Eun Jung Lee; Seong Yeon Park; Shi Nae Yu; Yu Mi Lee; Ki-Ho Park; Se Yoon Park; Min Hyok Jeon; Eun Ju Choo; Tae Hyong Kim; Mi Suk Lee Journal: Medicine (Baltimore) Date: 2018-10 Impact factor: 1.817
Authors: Tark Kim; Ki Ho Park; Shi Nae Yu; Seong Yeon Park; Se Yoon Park; Yu Mi Lee; Min Hyok Jeon; Eun Ju Choo; Tae Hyong Kim; Mi Suk Lee; EunJung Lee Journal: J Korean Med Sci Date: 2019-10-14 Impact factor: 2.153