| Literature DB >> 25735566 |
Giuseppe M Raffa1, Giuseppe D'Ancona1, Sergio Sciacca1, Astrid Pietrosi2, Cesar M Hernandez Baravoglia1, Marco Turrisi1, Giuseppe Romano1, Alessandro Armaro1, Vincenzo Stringi1, Francesco Clemenza1, Michele Pilato1.
Abstract
Endoventricular thrombolytic procedure (ETP) has been used to treat continuous-flow left ventricle assist device (CF-LVAD) thrombosis. The study aims to investigate the occurrence of complications after ETP. Data were retrospectively reviewed and analyzed in a series of patients who underwent CF-LVAD followed by ETP. Since November 2010, 20 patients underwent HeartWare CF-LVAD implantation at our institute. Four patients (20%) developed pump thrombosis and underwent a total of nine ETPs with tissue plasminogen activator infused into the left ventricle. The mean age was 60.2 ± 9 years. ETP was performed via either the femoral (n = 6) or radial artery (n = 3). Five ETPs (55.5%) were complicated by left and right radial artery occlusion, two by groin hematomas, and one by femoral artery false aneurysm. ETP carries a strong risk of vascular access complications that, in CF-LVAD patients, may add to the already complex clinical profile and economic burden; thus, a less invasive treatment is advisable whenever required.Entities:
Keywords: Continuous-flow pump; Thrombolysis; Vascular access-site complications
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Year: 2015 PMID： 25735566 DOI： 10.1111/aor.12423
Source DB: PubMed Journal: Artif Organs ISSN： 0160-564X Impact factor: 3.094