Literature DB >> 25733507

Influence of inflammation on voriconazole metabolism.

M A Encalada Ventura1, L F R Span2, E R van den Heuvel3, G M M Groothuis4, J-W C Alffenaar5.   

Abstract

Voriconazole pharmacokinetics shows a large inter- and intrapatient variability. Inflammation is associated with changes in the expression of CYP isoenzymes. Here, we evaluated the influence of inflammation, marked by C-reactive protein (CRP) levels in blood, on the metabolism of voriconazole. Observational data showed an association between CRP level and the ratio of voriconazole N-oxide to voriconazole.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID: 25733507      PMCID: PMC4394835          DOI: 10.1128/AAC.04789-14

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  12 in total

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Authors:  Thomas J Walsh; Elias J Anaissie; David W Denning; Raoul Herbrecht; Dimitrios P Kontoyiannis; Kieren A Marr; Vicki A Morrison; Brahm H Segal; William J Steinbach; David A Stevens; Jo-Anne van Burik; John R Wingard; Thomas F Patterson
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2.  Five year results of an international proficiency testing programme for measurement of antifungal drug concentrations.

Authors:  V J C Lempers; J W C Alffenaar; D J Touw; D M Burger; D R A Uges; R E Aarnoutse; R J M Brüggemann
Journal:  J Antimicrob Chemother       Date:  2014-07-07       Impact factor: 5.790

3.  The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: a randomized controlled trial.

Authors:  Wan Beom Park; Nak-Hyun Kim; Kye-Hyung Kim; Seung Hwan Lee; Won-Seok Nam; Seo Hyun Yoon; Kyoung-Ho Song; Pyoeng Gyun Choe; Nam Joong Kim; In-Jin Jang; Myoung-Don Oh; Kyung-Sang Yu
Journal:  Clin Infect Dis       Date:  2012-07-03       Impact factor: 9.079

Review 4.  Regulation of cytochromes P450 during inflammation and infection.

Authors:  E T Morgan
Journal:  Drug Metab Rev       Date:  1997-11       Impact factor: 4.518

5.  Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring.

Authors:  Michael J Dolton; John E Ray; Sharon C-A Chen; Kingsley Ng; Lisa G Pont; Andrew J McLachlan
Journal:  Antimicrob Agents Chemother       Date:  2012-07-02       Impact factor: 5.191

6.  Pharmacokinetics and safety of voriconazole following intravenous- to oral-dose escalation regimens.

Authors:  L Purkins; N Wood; P Ghahramani; K Greenhalgh; M J Allen; D Kleinermans
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

7.  Method for therapeutic drug monitoring of azole antifungal drugs in human serum using LC/MS/MS.

Authors:  J W C Alffenaar; A M A Wessels; K van Hateren; B Greijdanus; J G W Kosterink; D R A Uges
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2010-01-01       Impact factor: 3.205

8.  Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer.

Authors:  Edward T Morgan; Kerry B Goralski; Micheline Piquette-Miller; Kenneth W Renton; Graham R Robertson; Madhusudana R Chaluvadi; Kellie A Charles; Stephen J Clarke; Marina Kacevska; Christopher Liddle; Terrilyn A Richardson; Rohini Sharma; Christopher J Sinal
Journal:  Drug Metab Dispos       Date:  2008-02       Impact factor: 3.922

Review 9.  Clinical relevance of the pharmacokinetic interactions of azole antifungal drugs with other coadministered agents.

Authors:  Roger J M Brüggemann; Jan-Willem C Alffenaar; Nicole M A Blijlevens; Eliane M Billaud; Jos G W Kosterink; Paul E Verweij; David M Burger
Journal:  Clin Infect Dis       Date:  2009-05-15       Impact factor: 9.079

10.  Inflammation is associated with voriconazole trough concentrations.

Authors:  Marjolijn J P van Wanrooy; Lambert F R Span; Michael G G Rodgers; Edwin R van den Heuvel; Donald R A Uges; Tjip S van der Werf; Jos G W Kosterink; Jan-Willem C Alffenaar
Journal:  Antimicrob Agents Chemother       Date:  2014-09-15       Impact factor: 5.191

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  12 in total

Review 1.  Challenges in the Treatment of Invasive Aspergillosis in Immunocompromised Children.

Authors:  Alice J Hsu; Pranita D Tamma; Brian T Fisher
Journal:  Antimicrob Agents Chemother       Date:  2022-06-29       Impact factor: 5.938

2.  Impact of Obesity on Voriconazole Pharmacokinetics among Pediatric Hematopoietic Cell Transplant Recipients.

Authors:  Takuto Takahashi; Angela R Smith; Pamala A Jacobson; James Fisher; Nathan T Rubin; Mark N Kirstein
Journal:  Antimicrob Agents Chemother       Date:  2020-11-17       Impact factor: 5.191

Review 3.  Voriconazole: A Review of Population Pharmacokinetic Analyses.

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Journal:  Clin Pharmacokinet       Date:  2019-06       Impact factor: 6.447

4.  Longitudinal Analysis of the Effect of Inflammation on Voriconazole Trough Concentrations.

Authors:  M A Encalada Ventura; M J P van Wanrooy; L F R Span; M G G Rodgers; E R van den Heuvel; D R A Uges; T S van der Werf; J G W Kosterink; J W C Alffenaar
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

5.  The effect of inflammation on voriconazole trough concentrations in children.

Authors:  Mendy Ter Avest; Anette Veringa; Edwin R van den Heuvel; Jos G W Kosterink; Elisabeth H Schölvinck; Wim J E Tissing; Jan-Willem C Alffenaar
Journal:  Br J Clin Pharmacol       Date:  2016-11-09       Impact factor: 4.335

6.  Impact of Inflammation on Cytochromes P450 Activity in Pediatrics: A Systematic Review.

Authors:  Camille Lenoir; Frédérique Rodieux; Jules A Desmeules; Victoria Rollason; Caroline F Samer
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7.  Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.

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8.  Combined Impact of Inflammation and Pharmacogenomic Variants on Voriconazole Trough Concentrations: A Meta-Analysis of Individual Data.

Authors:  Léa Bolcato; Charles Khouri; Anette Veringa; Jan Willem C Alffenaar; Takahiro Yamada; Takafumi Naito; Fabien Lamoureux; Xavier Fonrose; Françoise Stanke-Labesque; Elodie Gautier-Veyret
Journal:  J Clin Med       Date:  2021-05-13       Impact factor: 4.241

9.  Moderate correlation between systemic IL-6 responses and CRP with trough concentrations of voriconazole.

Authors:  Bas Vreugdenhil; Walter J F M van der Velden; Ton Feuth; Matthijs Kox; Peter Pickkers; Frank L van de Veerdonk; Nicole M A Blijlevens; Roger J M Brüggemann
Journal:  Br J Clin Pharmacol       Date:  2018-06-19       Impact factor: 4.335

Review 10.  Inflammation is a major regulator of drug metabolizing enzymes and transporters: Consequences for the personalization of drug treatment.

Authors:  Françoise Stanke-Labesque; Elodie Gautier-Veyret; Stephanie Chhun; Romain Guilhaumou
Journal:  Pharmacol Ther       Date:  2020-07-11       Impact factor: 12.310

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