Literature DB >> 25732719

Safety of Non-anesthesia Provider-Administered Propofol (NAAP) Sedation in Advanced Gastrointestinal Endoscopic Procedures: Comparative Meta-Analysis of Pooled Results.

Basavana Gouda Goudra1, Preet Mohinder Singh, Gowri Gouda, Anuradha Borle, Divakara Gouda, Amulya Dravida, Vinay Chandrashakhara.   

Abstract

BACKGROUND AND AIMS: The aim of the study was to evaluate the safety of non-anesthesia provider (NAAP)-administered propofol sedation for advanced endoscopic procedures with those of anesthesia provider (AAP).
METHODS: PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Scopus, and Web of Science databases were searched for prospective observational trials involving advanced endoscopic procedures. From a total of 519 publications, 26 were identified to meet inclusion criteria (10 AAPs and 16 NAAPs) and were analyzed. Data were analyzed for hypoxia rate, airway intervention rates, endoscopist, and patient satisfaction scores and total propofol administered.
RESULTS: Total number of procedures in NAAP and AAP groups was 3018 and 2374, respectively. Pooled hypoxia (oxygen saturation less than 90 %) rates were 0.133 (95 % CI 0.117-0.152) and 0.143 (95 % CI 0.128-0.159) in NAAP and AAP, respectively. Similarly, pooled airway intervention rates were 0.035 (95 % CI 0.026-0.047) and 0.133 (95 % CI 0.118-0.150), respectively. Pooled patient satisfaction rate, pooled endoscopist satisfaction rate, and mean propofol administered dose for NAAP were 7.22 (95 % CI 7.17-7.27), 6.03 (95 % CI 5.94-6.11), and 251.44 mg (95 % CI 244.39-258.49) in that order compared with 9.82 (95 % CI 9.76-9.88), 9.06 (95 % CI 8.91-9.21), and 340.32 mg (95 % CI 327.30-353.33) for AAP.
CONCLUSIONS: The safety of NAAP sedation compared favorably with AAP sedation in patients undergoing advanced endoscopic procedures. However, it came at the cost of decreased patient and endoscopist satisfaction.

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Year:  2015        PMID: 25732719     DOI: 10.1007/s10620-015-3608-x

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  42 in total

Review 1.  SEDASYS(®), airway, oxygenation, and ventilation: anticipating and managing the challenges.

Authors:  Basavana Gouda Goudra; Preet Mohinder Singh; Vinay Chandrasekhara
Journal:  Dig Dis Sci       Date:  2014-01-08       Impact factor: 3.199

2.  Deep sedation without intubation for ERCP is appropriate in healthier, non-obese patients.

Authors:  Sheila Ryan Barnett; Tyler Berzin; Sirish Sanaka; Douglas Pleskow; Mandeep Sawhney; Ram Chuttani
Journal:  Dig Dis Sci       Date:  2013-07-23       Impact factor: 3.199

3.  Bispectral index monitoring of midazolam and propofol sedation during endoscopic retrograde cholangiopancreatography: a randomized clinical trial (the EndoBIS study).

Authors:  S von Delius; H Salletmaier; A Meining; S Wagenpfeil; D Saur; M Bajbouj; G Schneider; R M Schmid; W Huber
Journal:  Endoscopy       Date:  2012-01-19       Impact factor: 10.093

4.  Balanced propofol sedation versus propofol monosedation in therapeutic pancreaticobiliary endoscopic procedures.

Authors:  Tae Hoon Lee; Chang Kyun Lee; Sang-Heum Park; Suck-Ho Lee; Il-Kwun Chung; Hyun Jong Choi; Sang Woo Cha; Jong Ho Moon; Young Deok Cho; Young Hwangbo; Sun-Joo Kim
Journal:  Dig Dis Sci       Date:  2012-05-22       Impact factor: 3.199

5.  Gastroenterologist-guided sedation with propofol for endoscopic ultrasonography in average-risk and high-risk patients: a prospective series.

Authors:  Eduardo Redondo-Cerezo; Antonio Sánchez-Robaina; Juan Gabriel Martínez Cara; Manuel Ojeda-Hinojosa; Ana Matas-Cobos; Antonio Damián Sánchez Capilla; Mercedes López de Hierro Ruíz; Julio Pleguezuelo-Díaz; Javier de Teresa
Journal:  Eur J Gastroenterol Hepatol       Date:  2012-05       Impact factor: 2.566

6.  Incidence of sedation-related complications with propofol use during advanced endoscopic procedures.

Authors:  Gregory A Coté; Robert M Hovis; Michael A Ansstas; Lawrence Waldbaum; Riad R Azar; Dayna S Early; Steven A Edmundowicz; Daniel K Mullady; Sreenivasa S Jonnalagadda
Journal:  Clin Gastroenterol Hepatol       Date:  2009-07-14       Impact factor: 11.382

7.  Electroencephalogram monitoring facilitates sedation with propofol for routine ERCP: a randomized, controlled trial.

Authors:  Till Wehrmann; Jörg Grotkamp; Nikos Stergiou; Andrea Riphaus; Annegret Kluge; Bernhard Lembcke; Arthur Schultz
Journal:  Gastrointest Endosc       Date:  2002-12       Impact factor: 9.427

8.  Propofol infusion versus intermittent meperidine and midazolam injection for conscious sedation in ERCP.

Authors:  Pradermchai Kongkam; Rungsun Rerknimitr; Sahadol Punyathavorn; Chitr Sitthi-Amorn; Yuwadee Ponauthai; Narongrit Prempracha; Pinit Kullavanijaya
Journal:  J Gastrointestin Liver Dis       Date:  2008-09       Impact factor: 2.008

9.  Safety of nonanesthetist sedation with propofol for outpatient colonoscopy and esophagogastroduodenoscopy.

Authors:  D Külling; R Rothenbühler; W Inauen
Journal:  Endoscopy       Date:  2003-08       Impact factor: 10.093

Review 10.  Endoscopist-directed administration of propofol: a worldwide safety experience.

Authors:  Douglas K Rex; Viju P Deenadayalu; Emely Eid; Thomas F Imperiale; John A Walker; Kuldip Sandhu; Anthony C Clarke; Lybus C Hillman; Akira Horiuchi; Lawrence B Cohen; Ludwig T Heuss; Shajan Peter; Christoph Beglinger; James A Sinnott; Thomas Welton; Magdy Rofail; Iyad Subei; Rodger Sleven; Paul Jordan; John Goff; Patrick D Gerstenberger; Harold Munnings; Martin Tagle; Brian W Sipe; Till Wehrmann; Jack A Di Palma; Kaitlin E Occhipinti; Egidio Barbi; Andrea Riphaus; Stephen T Amann; Gen Tohda; Timothy McClellan; Charles Thueson; John Morse; Nizam Meah
Journal:  Gastroenterology       Date:  2009-06-21       Impact factor: 22.682

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  20 in total

Review 1.  Current role of non-anesthesiologist administered propofol sedation in advanced interventional endoscopy.

Authors:  Daniela Elena Burtea; Anca Dimitriu; Anca Elena Maloş; Adrian Săftoiu
Journal:  World J Gastrointest Endosc       Date:  2015-08-10

2.  Anesthesiologist-Administered Gastrointestinal Sedation: Time to Put It to Sleep?

Authors:  Kilian Friedrich; Wolfgang Stremmel
Journal:  Dig Dis Sci       Date:  2015-05-19       Impact factor: 3.199

3.  Big Sleep: Beyond Propofol Sedation During GI Endoscopy.

Authors:  Basavana Goudra
Journal:  Dig Dis Sci       Date:  2019-01       Impact factor: 3.199

4.  Propofol administration by endoscopists versus anesthesiologists in gastrointestinal endoscopy: a systematic review and meta-analysis of patient safety outcomes.

Authors:  Julian F Daza; Carolyn M Tan; Ryan J Fielding; Allison Brown; Forough Farrokhyar; Ilun Yang
Journal:  Can J Surg       Date:  2018-08       Impact factor: 2.089

Review 5.  Optimizing Prophylactic CPAP in Patients Without Obstructive Sleep Apnoea for High-Risk Abdominal Surgeries: A Meta-regression Analysis.

Authors:  Preet Mohinder Singh; Anuradha Borle; Dipal Shah; Ashish Sinha; Jeetinder Kaur Makkar; Anjan Trikha; Basavana Gouda Goudra
Journal:  Lung       Date:  2016-02-19       Impact factor: 2.584

6.  Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells.

Authors:  Zhiwei Shang; Haixia Feng; Lisha Cui; Weiping Wang; Hongwei Fu
Journal:  Oncol Lett       Date:  2017-10-31       Impact factor: 2.967

7.  Propofol administration by endoscopists versus anesthesiologists in gastrointestinal endoscopy: a systematic review and meta-analysis of patient safety outcomes.

Authors:  Julian F Daza; Carolyn M Tan; Ryan J Fielding; Allison Brown; Forough Farrokhyar; Ilun Yang
Journal:  Can J Surg       Date:  2018-06-01       Impact factor: 2.089

8.  Controversies in ERCP: Indications and preparation.

Authors:  Christoph F Dietrich; Noor L Bekkali; Sean Burmeister; Yi Dong; Simon M Everett; Michael Hocke; Andre Ignee; Wei On; Srisha Hebbar; Kofi Oppong; Siyu Sun; Christian Jenssen; Barbara Braden
Journal:  Endosc Ultrasound       Date:  2022 May-Jun       Impact factor: 5.275

9.  Repetitive Transcranial Magnetic Stimulation in Chronic Pain: A Meta-analysis.

Authors:  Basavana Goudra; Dipal Shah; Ganesh Balu; Gowri Gouda; Alan Balu; Anuradha Borle; Preet Mohinder Singh
Journal:  Anesth Essays Res       Date:  2017 Jul-Sep

10.  High efficacy with deep nurse-administered propofol sedation for advanced gastroenterologic endoscopic procedures.

Authors:  Jeppe Thue Jensen; Pernille Hornslet; Lars Konge; Ann Merete Møller; Peter Vilmann
Journal:  Endosc Int Open       Date:  2015-12-07
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