| Literature DB >> 25732646 |
Aydin Sav1, Fabio Rotondo2, Luis V Syro3, Antonio Di Ieva4, Michael D Cusimano4, Kalman Kovacs2.
Abstract
Aggressive pituitary adenomas have a high risk of recurrence, a lack of therapeutic response, and resistance to conventional treatment. So far, no satisfactory biomarkers are available for predicting their behavior. Some specific pituitary adenoma histotypes are more prone to follow an aggressive behavior. Pituitary carcinomas are rare and show cerebrospinal and/or systemic metastasis. They have worse prognosis than aggressive adenomas, and radiation is of limited use in their treatment.Entities:
Keywords: Aggressive pituitary adenoma; Atypical adenoma; Diagnosis; Invasive adenoma; Noninvasive adenoma; Pituitary carcinoma
Mesh：
Year: 2014 PMID： 25732646 DOI： 10.1016/j.ecl.2014.10.008
Source DB: PubMed Journal: Endocrinol Metab Clin North Am ISSN： 0889-8529 Impact factor: 4.741