PURPOSE: To report lung parenchymal findings on high-resolution computed tomography (HRCT) in a population of asymptomatic, never-smoker urban dwellers aged 65 years and older. MATERIALS AND METHODS: After institutional approval, asymptomatic older patients from the Geriatrics Outpatient Clinic aged 65 years and older (older group) and healthy volunteers aged 30-50 years (younger group) were invited to participate in the study. Asymptomatic, never-smoker subjects considered free of relevant disease after spirometry and echocardiography underwent chest HRCT. Three researchers reviewed every scan, noting the absence/presence and distribution of pre-specified parenchymal findings. Statistical comparisons between groups were performed using appropriate tests with the aid of software. RESULTS: Forty-seven older and 24 younger subjects were included in this analysis. A higher proportion of women and a longer history of urban dwelling were present in the older group. Parenchymal findings were more prevalent in the older group (78.7 vs. 25% in the younger group; p < 0.001). Parenchymal bands (59.6 vs. 25%; p = 0.007), ground-glass opacities (25.5 vs. 0%; p = 0.006), and septal lines (21.3 vs. 0%; p = 0.013) were more prevalent in the elderly. When only subjects aged 75 years and older were considered as the older group, micronodules, reticular opacities, cysts, and bronchiectases (19.1 vs. 0 % for all comparisons; p = 0.04) were also more frequently found among the elderly. CONCLUSION: Parenchymal bands, ground-glass opacities, septal lines, bronchiectasis, micronodules, reticular opacities, and lung cysts were more prevalent among the elderly.
PURPOSE: To report lung parenchymal findings on high-resolution computed tomography (HRCT) in a population of asymptomatic, never-smoker urban dwellers aged 65 years and older. MATERIALS AND METHODS: After institutional approval, asymptomatic older patients from the Geriatrics Outpatient Clinic aged 65 years and older (older group) and healthy volunteers aged 30-50 years (younger group) were invited to participate in the study. Asymptomatic, never-smoker subjects considered free of relevant disease after spirometry and echocardiography underwent chest HRCT. Three researchers reviewed every scan, noting the absence/presence and distribution of pre-specified parenchymal findings. Statistical comparisons between groups were performed using appropriate tests with the aid of software. RESULTS: Forty-seven older and 24 younger subjects were included in this analysis. A higher proportion of women and a longer history of urban dwelling were present in the older group. Parenchymal findings were more prevalent in the older group (78.7 vs. 25% in the younger group; p < 0.001). Parenchymal bands (59.6 vs. 25%; p = 0.007), ground-glass opacities (25.5 vs. 0%; p = 0.006), and septal lines (21.3 vs. 0%; p = 0.013) were more prevalent in the elderly. When only subjects aged 75 years and older were considered as the older group, micronodules, reticular opacities, cysts, and bronchiectases (19.1 vs. 0 % for all comparisons; p = 0.04) were also more frequently found among the elderly. CONCLUSION: Parenchymal bands, ground-glass opacities, septal lines, bronchiectasis, micronodules, reticular opacities, and lung cysts were more prevalent among the elderly.
Authors: David M Hansell; Alexander A Bankier; Heber MacMahon; Theresa C McLoud; Nestor L Müller; Jacques Remy Journal: Radiology Date: 2008-01-14 Impact factor: 11.105
Authors: Sherif F Nagueh; Christopher P Appleton; Thierry C Gillebert; Paolo N Marino; Jae K Oh; Otto A Smiseth; Alan D Waggoner; Frank A Flachskampf; Patricia A Pellikka; Arturo Evangelista Journal: J Am Soc Echocardiogr Date: 2009-02 Impact factor: 5.251
Authors: David A Lynch; William D Travis; Nestor L Müller; Jeffrey R Galvin; David M Hansell; Philippe A Grenier; Talmadge E King Journal: Radiology Date: 2005-07 Impact factor: 11.105
Authors: Tetsuro Araki; Mizuki Nishino; Wei Gao; Josée Dupuis; Rachel K Putman; George R Washko; Gary M Hunninghake; George T O'Connor; Hiroto Hatabu Journal: Thorax Date: 2015-10-29 Impact factor: 9.139
Authors: James D Chalmers; Stefano Aliberti; Eva Polverino; Montserrat Vendrell; Megan Crichton; Michael Loebinger; Katerina Dimakou; Ian Clifton; Menno van der Eerden; Gernot Rohde; Marlene Murris-Espin; Sarah Masefield; Eleanor Gerada; Michal Shteinberg; Felix Ringshausen; Charles Haworth; Wim Boersma; Jessica Rademacher; Adam T Hill; Timothy Aksamit; Anne O'Donnell; Lucy Morgan; Branislava Milenkovic; Leandro Tramma; Joao Neves; Rosario Menendez; Perluigi Paggiaro; Victor Botnaru; Sabina Skrgat; Robert Wilson; Pieter Goeminne; Anthony De Soyza; Tobias Welte; Antoni Torres; J Stuart Elborn; Francesco Blasi Journal: ERJ Open Res Date: 2016-01-20
Authors: Anna Elisabeth Frick; Hendrik Jan Ankersmit; Ingrid Simonitsch-Klupp; Konrad Hoetzenecker Journal: Interact Cardiovasc Thorac Surg Date: 2022-06-01