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Literature DB >> 25731

Immunoreactive properties of anti-thyroglobulin autoantibodies isolated by affinity chromatography from human thyroiditis serum.

Abstract

A Sepharose-coupled 19S human thyroglobulin has been used as an immunoadsorbent to isolate anti-thyroglobulin autoantibodies and to evaluate the antigen-antibody interactions. With the system proposed a high yield of active antibody molecules was obtained. It is possible to evaluate both the soluble and precipitating 'immunological interactions', thus avoiding the use of the double antibody technique.

Entities: Chemical Disease Species

Mesh：

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Year: 1978 PMID： 25731 PMCID： PMC1541229

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

13 in total

1. LABELLING OF HUMAN FIBRINOGEN WITH 131-I BY ELECTROLYTIC IODINATION.

Authors: U ROSA; G A SCASSELLATI; F PENNISI
Journal: Biochim Biophys Acta Date: 1964-06-08

2. Purification of anti-thyroglobin antibodies.

Authors: H METZGER; H EDELHOCH
Journal: Nature Date: 1962-01-20 Impact factor: 49.962

3. Identification in the thyroid of antithyroglobulin antibodies in the fibrous variant of Hashimoto's thyroiditis.

Authors: G B Salabè; C Davoli; M Andreoli
Journal: Int Arch Allergy Appl Immunol Date: 1974

4. The immunoreaction of auto- and heteroantisera with modified human thyroglobulin.

Authors: G B Salabè; C Davoli; S Fontana
Journal: Int Arch Allergy Appl Immunol Date: 1973

5. Quantitative estimation of antibodies in different immunoglobulin classes.

Authors: G Torrigiani; I M Roitt
Journal: J Immunol Date: 1969-02 Impact factor: 5.422

6. Effect of iodide concentration on thyroxine synthesis catalysed by thyroid peroxidase.

Authors: J Pommier; D Deme; J Nunez
Journal: Eur J Biochem Date: 1973-09-03

Review 7. On the specificity of antibodies.

Authors: F F Richards; W H Konigsberg; R W Rosenstein; J M Varga
Journal: Science Date: 1975-01-17 Impact factor: 47.728

Immunoreactive properties of anti-thyroglobulin autoantibodies isolated by affinity chromatography from human thyroiditis serum.

1. LABELLING OF HUMAN FIBRINOGEN WITH 131-I BY ELECTROLYTIC IODINATION.

2. Purification of anti-thyroglobin antibodies.

3. Identification in the thyroid of antithyroglobulin antibodies in the fibrous variant of Hashimoto's thyroiditis.

4. The immunoreaction of auto- and heteroantisera with modified human thyroglobulin.

5. Quantitative estimation of antibodies in different immunoglobulin classes.

6. Effect of iodide concentration on thyroxine synthesis catalysed by thyroid peroxidase.

Review 7. On the specificity of antibodies.

8. Radioimmunoassay for human antithyroglobulin antibodies. II. Determination of antigen-binding capacity.

9. Isolation of hetero antibodies to human thyroglobulin.

10. Effect of electrolytes and of distilled water on antigen-antibody complexes.

1. Evidence of unique idiotypic determinants and similar idiotypic determinants on human antithyroglobulin antibodies.