Literature DB >> 25730924

Schedules of controlled substances: temporary placement of three synthetic cannabinoids into schedule I. Final order.

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Abstract

The Administrator of the Drug Enforcement Administration is issuing this final order to temporarily schedule three synthetic cannabinoids (SCs) into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act (CSA). The substances are: (1) N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide ("AB-CHMINACA''); (2) N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide ("AB-PINACA''); and (3) [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone ("THJ-2201''). This action is based on a finding by the Administrator that the placement of these synthetic cannabinoids and their optical, positional, and geometric isomers, salts, and salts of isomers into schedule I of the CSA is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, import, export, engage in research, or possess), or propose to handle these SCs.

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Year:  2015        PMID: 25730924

Source DB:  PubMed          Journal:  Fed Regist        ISSN: 0097-6326


  8 in total

1.  Thermolytic Degradation of Synthetic Cannabinoids: Chemical Exposures and Pharmacological Consequences.

Authors:  Brian F Thomas; Timothy W Lefever; Ricardo A Cortes; Megan Grabenauer; Alexander L Kovach; Anderson O Cox; Purvi R Patel; Gerald T Pollard; Julie A Marusich; Richard C Kevin; Thomas F Gamage; Jenny L Wiley
Journal:  J Pharmacol Exp Ther       Date:  2017-01-13       Impact factor: 4.030

2.  Death Associated With the Use of the Synthetic Cannabinoid ADB-FUBINACA.

Authors:  Kevin G Shanks; William Clark; George Behonick
Journal:  J Anal Toxicol       Date:  2016-01-10       Impact factor: 3.367

3.  AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice.

Authors:  Jenny L Wiley; Julie A Marusich; Timothy W Lefever; Kateland R Antonazzo; Michael T Wallgren; Ricardo A Cortes; Purvi R Patel; Megan Grabenauer; Katherine N Moore; Brian F Thomas
Journal:  J Pharmacol Exp Ther       Date:  2015-06-23       Impact factor: 4.030

Review 4.  Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review.

Authors:  Elisabet Navarro-Tapia; Jana Codina; Víctor José Villanueva-Blasco; Óscar García-Algar; Vicente Andreu-Fernández
Journal:  Biology (Basel)       Date:  2022-05-23

5.  An outbreak of acute delirium from exposure to the synthetic cannabinoid AB-CHMINACA.

Authors:  Joseph A Tyndall; Roy Gerona; Giuliano De Portu; Jordan Trecki; Marie-Carmelle Elie; Judith Lucas; John Slish; Kenneth Rand; Lindsay Bazydlo; Martina Holder; Matthew F Ryan; Paul Myers; Nicole Iovine; Michelle Plourde; Emily Weeks; James R Hanley; Greg Endres; Danielle St Germaine; Paul J Dobrowolski; Michael Schwartz
Journal:  Clin Toxicol (Phila)       Date:  2015-11-10       Impact factor: 3.738

Review 6.  Emerging drugs of abuse: current perspectives on synthetic cannabinoids.

Authors:  Danièle Debruyne; Reynald Le Boisselier
Journal:  Subst Abuse Rehabil       Date:  2015-10-20

7.  The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities.

Authors:  Mitchell Longworth; Samuel D Banister; James B C Mack; Michelle Glass; Mark Connor; Michael Kassiou
Journal:  Forensic Toxicol       Date:  2016-04-27       Impact factor: 4.096

8.  Determination of in vitro human whole blood-to-plasma ratio of THJ-018 utilizing gas chromatography-Mass spectrometry.

Authors:  Sachil Kumar; Remal Nahar Khleel Alkhibery; Abdulsallam Bakdash; Mohamed Sultan Mohamed Abdelhady
Journal:  Indian J Pharmacol       Date:  2021 Jan-Feb       Impact factor: 1.200

  8 in total

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