Literature DB >> 25727833

Congenital tuberculosis: presentation of a rare case.

Velat Şen1, Hadice Selimoğlu Şen1, Fesih Aktar1, Ünal Uluca1, Müsemma Karabel1, Mehmet Fuat Gürkan1.   

Abstract

Congenital tuberculosis is a rare disease with a high mortality rate. Congenital tuberculosis is considered the result of mother-to-child transmission from the placenta to the fetus, through the ingestion of the amniotic fluid, or via transplacental transmission through the umbilical vein. Given the non-specific clinical signs of tuberculosis, it is usually difficult to diagnose it. The case of a 48-day-old male infant hospitalized due to weight loss, fever, cough, hemoptysis, and respiratory distress for the past 20 days, is presented. In this period, he had received broad spectrum antibiotics but with no improvement. A chest x-ray showed the presence of consolidation and a cavitary lesion in the upper and middle left lung fields. Mycobacterium tuberculosis was detected by polymerase chain reaction in a bronchoalveolar lavage specimen. Congenital tuberculosis was diagnosed based on this finding; hence, a tuberculostatic regimen was started accordingly. The patient died 13 days after treatment initiation. Congenital tuberculosis should be considered in infants with weight loss, fever, cough, hemoptysis and respiratory distress.

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Year:  2015        PMID: 25727833     DOI: 10.5546/aap.2015.eng.e101

Source DB:  PubMed          Journal:  Arch Argent Pediatr        ISSN: 0325-0075            Impact factor:   0.694


  3 in total

Review 1.  A Perspective of the Diagnosis and Management of Congenital Tuberculosis.

Authors:  Manou Irmina Saramba; Dongchi Zhao
Journal:  J Pathog       Date:  2016-11-24

Review 2.  Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases.

Authors:  Chaofeng Li; Lili Liu; Yuhong Tao
Journal:  Orphanet J Rare Dis       Date:  2019-06-10       Impact factor: 4.123

3.  A Case of Miliary Perinatal Tuberculosis in a Preterm Newborn Infant Presenting as Peritonitis.

Authors:  Artsiom Klimko; Alienor Brandt; Maria-Iulia Brustan
Journal:  Cureus       Date:  2020-05-09
  3 in total

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