Literature DB >> 25727735

Four new cytotoxic xanthones from Garcinia nujiangensis.

Zhong-Yan Tang1, Zheng-Xiang Xia2, Shi-Ping Qiao1, Chao Jiang1, Guo-Rong Shen1, Mei-Xiang Cai3, Xiao-Yan Tang4.   

Abstract

Bioassay-guided fractionation of the acetone extract of the twigs of Garcinia nujiangensis resulted in the isolation of four new prenylated xanthones, nujiangexanthones C-F (1-4), and ten known related analogues. The structures of compounds 1-4 were elucidated by interpretation of their spectroscopic data. The compounds isolated were evaluated for their cytotoxic effects against three cancer cell lines, the test substances demonstrated selectivity toward the cancer cells.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cudratricusxanthone E (Pubchem CID: 49799569); Cytotoxic; Etoposide I (Pubchem CID: 36462); Garcihombronone B (Pubchem CID: 44559190); Garcinia nujiangensis; Guttiferone F (Pubchem CID: 5352099); Jacareubin (Pubchem CID: 5281644); Nujiangefolin A (Pubchem CID: 66553664); Nujiangefolin B (Pubchem CID: 66553665); Nujiangexanthone A (Pubchem CID: 66553581); Nujiangexanthone B (Pubchem CID: 66553663); Stachyline C (Pubchem CID: 50993978); Xanthone

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Year:  2015        PMID: 25727735     DOI: 10.1016/j.fitote.2015.02.011

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


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2.  Regulation of MAPKs Signaling Contributes to the Growth Inhibition of 1,7-Dihydroxy-3,4-dimethoxyxanthone on Multidrug Resistance A549/Taxol Cells.

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Journal:  Drug Des Devel Ther       Date:  2020-09-25       Impact factor: 4.162

4.  Acylphloroglucinol Derivatives from Garcinia multiflora with Anti-Inflammatory Effect in LPS-Induced RAW264.7 Macrophages.

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Journal:  Molecules       Date:  2018-10-10       Impact factor: 4.411

Review 5.  Chemical and Biological Research on Herbal Medicines Rich in Xanthones.

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Journal:  Molecules       Date:  2017-10-11       Impact factor: 4.411

Review 6.  Medicinal Potential of Garcinia Species and Their Compounds.

Authors:  Bruna Larissa Spontoni do Espirito Santo; Lidiani Figueiredo Santana; Wilson Hino Kato Junior; Felipe de Oliveira de Araújo; Danielle Bogo; Karine de Cássia Freitas; Rita de Cássia Avellaneda Guimarães; Priscila Aiko Hiane; Arnildo Pott; Wander Fernando de Oliveira Filiú; Marcel Arakaki Asato; Patrícia de Oliveira Figueiredo; Paulo Roberto Haidamus de Oliveira Bastos
Journal:  Molecules       Date:  2020-10-01       Impact factor: 4.411

  6 in total

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