| Literature DB >> 25727710 |
Sima Majidi1,2, Fatemeh Zeinali Sehrig1,2, Mohammad Samiei1,3, Morteza Milani4,1, Elham Abbasi4,1, Kianoosh Dadashzadeh5, Abolfazl Akbarzadeh4,1.
Abstract
Gene therapy is defined as the direct transfer of genetic material to tissues or cells for the treatment of inherited disorders and acquired diseases. For gene delivery, magnetic nanoparticles (MNPs) are typically combined with a delivery platform to encapsulate the gene, and promote cell uptake. Delivery technologies that have been used with MNPs contain polymeric, viral, as well as non-viral platforms. In this review, we focus on targeted gene delivery using MNPs.Entities:
Keywords: cell uptake; gene therapy; magnetic nanoparticles; non-viral platforms
Mesh:
Year: 2015 PMID: 25727710 DOI: 10.3109/21691401.2015.1014093
Source DB: PubMed Journal: Artif Cells Nanomed Biotechnol ISSN: 2169-1401 Impact factor: 5.678