Literature DB >> 2572653

Hepatitis A virus infection in a chimpanzee: duration of viremia and detection of virus in saliva and throat swabs.

J I Cohen1, S Feinstone, R H Purcell.   

Abstract

The pathogenesis of hepatitis A virus was studied by orally inoculating a chimpanzee with wild-type virus. The virus was initially detected in the animal's serum (day 14 after inoculation); then viral antigen was detected in the tonsils (day 16), virus in the saliva and throat swabs (day 18), and viral antigen in the liver (day 21). The animal was viremic for 2 w. While this study involved a single animal, the presence of hepatitis A virus in saliva and throat swabs suggests a possible oropharyngeal site for viral replication.

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Year:  1989        PMID: 2572653     DOI: 10.1093/infdis/160.5.887

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  12 in total

Review 1.  Diagnosis of hepatitis a virus infection: a molecular approach.

Authors:  Omana V Nainan; Guoliang Xia; Gilberto Vaughan; Harold S Margolis
Journal:  Clin Microbiol Rev       Date:  2006-01       Impact factor: 26.132

Review 2.  [Sexually transmissible hepatitis viruses].

Authors:  S Schaefer
Journal:  Hautarzt       Date:  2009-06       Impact factor: 0.751

3.  Seroepidemiology of hepatitis A virus in Kuwait.

Authors:  Jameela Alkhalidi; Bader Alenezi; Seham Al-Mufti; Entisar Hussain; Haifa Askar; Nyingi Kemmer; Guy W Neff
Journal:  World J Gastroenterol       Date:  2009-01-07       Impact factor: 5.742

4.  Chimpanzees as an animal model for human norovirus infection and vaccine development.

Authors:  Karin Bok; Gabriel I Parra; Tanaji Mitra; Eugenio Abente; Charlene K Shaver; Denali Boon; Ronald Engle; Claro Yu; Albert Z Kapikian; Stanislav V Sosnovtsev; Robert H Purcell; Kim Y Green
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-20       Impact factor: 11.205

Review 5.  Nonhuman Primate Models of Hepatitis A Virus and Hepatitis E Virus Infections.

Authors:  Robert E Lanford; Christopher M Walker; Stanley M Lemon
Journal:  Cold Spring Harb Perspect Med       Date:  2019-02-01       Impact factor: 6.915

6.  Hepatitis A virus-specific immunoglobulin A mediates infection of hepatocytes with hepatitis A virus via the asialoglycoprotein receptor.

Authors:  A Dotzauer; U Gebhardt; K Bieback; U Göttke; A Kracke; J Mages; S M Lemon; A Vallbracht
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

7.  Experimental hepatitis A virus (HAV) infection in cynomolgus monkeys (Macaca fascicularis): evidence of active extrahepatic site of HAV replication.

Authors:  Luciane A Amado; Renato S Marchevsky; Vanessa S de Paula; Cleber Hooper; Marcos da S Freire; Ana Maria C Gaspar; Marcelo A Pinto
Journal:  Int J Exp Pathol       Date:  2010-02       Impact factor: 1.925

8.  The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor.

Authors:  D Feigelstock; P Thompson; P Mattoo; Y Zhang; G G Kaplan
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

9.  Seroprevalence and Molecular Characterisation of Human Hepatitis A virus in Serum Samples of Tunisian Patients with Clinical Symptoms of Viral Hepatitis.

Authors:  Hakima Gharbi-Khelifi; Nabil Ben Salem Abid; Abir Beji; Leila Bhiri; Rafik Harrath; Khira Sdiri; Sylviane Billaudel; Virginie Ferre; Mahjoub Aouni
Journal:  Indian J Virol       Date:  2012-03-25

10.  Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020.

Authors:  Noele P Nelson; Mark K Weng; Megan G Hofmeister; Kelly L Moore; Mona Doshani; Saleem Kamili; Alaya Koneru; Penina Haber; Liesl Hagan; José R Romero; Sarah Schillie; Aaron M Harris
Journal:  MMWR Recomm Rep       Date:  2020-07-03
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