Dae-Hyung Lee1, Dong Bin Kim2, Hyun Yong Kim1, Hyun Sook Baek1, Soon-Young Kwon2, Mi Hee Lee2, Jong-Chul Park3. 1. Medical Technology and Quality Evaluation Center, Severance Hospital, Seoul, Korea. 2. Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine, Seoul, Korea. 3. Medical Technology and Quality Evaluation Center, Severance Hospital, Seoul, Korea; Cellbiocontrol Laboratory, Department of Medical Engineering, Yonsei University College of Medicine, Seoul, Korea. Electronic address: parkjc@yuhs.ac.
Abstract
BACKGROUND: Medical devices inserted into the human body can be divided into single-use devices and reusable medical devices (RMDs) depending on the method of use. RMDs are applied to >1 patient, and users reprocess them prior to repeat use. Therefore, reprocessing of RMDs has become more difficult, and issues related to infection risk have become more prevalent. METHODS: Research was performed to compare differences in surface alterations between not-aged (NA) samples and accelerated-aging (AA) samples. NA and AA samples were exposed to potential contaminants and treated with the same cleaning conditions. Then the residual contaminants were analyzed, and adhesion characteristics were investigated. RESULTS: Significant differences between the 2 sample groups were observed in the pattern of physical surface alterations. Similar to the endoscope for clinical use, a deep crack was found in the surface of the AA sample. According to the binding affinity test, highly likely potential contaminants were found more frequently on AA samples. CONCLUSION: The results suggest the necessity of limiting the duration of time that RMDs may be used, considering the potential risk of infection from repetitive use of RMDs, and also raised the possibility of applying this simulation model of AA. This methodology can be applied to various RMDs, including endoscopes.
BACKGROUND: Medical devices inserted into the human body can be divided into single-use devices and reusable medical devices (RMDs) depending on the method of use. RMDs are applied to >1 patient, and users reprocess them prior to repeat use. Therefore, reprocessing of RMDs has become more difficult, and issues related to infection risk have become more prevalent. METHODS: Research was performed to compare differences in surface alterations between not-aged (NA) samples and accelerated-aging (AA) samples. NA and AA samples were exposed to potential contaminants and treated with the same cleaning conditions. Then the residual contaminants were analyzed, and adhesion characteristics were investigated. RESULTS: Significant differences between the 2 sample groups were observed in the pattern of physical surface alterations. Similar to the endoscope for clinical use, a deep crack was found in the surface of the AA sample. According to the binding affinity test, highly likely potential contaminants were found more frequently on AA samples. CONCLUSION: The results suggest the necessity of limiting the duration of time that RMDs may be used, considering the potential risk of infection from repetitive use of RMDs, and also raised the possibility of applying this simulation model of AA. This methodology can be applied to various RMDs, including endoscopes.
Authors: Gheorghe G Balan; Irina Rosca; Elena-Laura Ursu; Adrian Fifere; Cristian-Dragos Varganici; Florica Doroftei; Ioana-Andreea Turin-Moleavin; Vasile Sandru; Gabriel Constantinescu; Daniel Timofte; Gabriela Stefanescu; Anca Trifan; Catalin Victor Sfarti Journal: Molecules Date: 2019-06-25 Impact factor: 4.411
Authors: Marco J Bruno; Margreet C Vos; Arjan W Rauwers; Anne F Voor In 't Holt; Jolanda G Buijs; Woutrinus de Groot; Bettina E Hansen Journal: Gut Date: 2018-04-10 Impact factor: 23.059