Literature DB >> 25725562

Biodegradable poly-lactic acid based-composite reinforced unidirectionally with high-strength magnesium alloy wires.

X Li1, C L Chu2, L Liu1, X K Liu1, J Bai3, C Guo1, F Xue1, P H Lin1, Paul K Chu4.   

Abstract

Biodegradable poly-lactic acid (PLA)--based composites reinforced unidirectionally with high-strength magnesium alloy wires (MAWs) are fabricated by a heat-compressing process and the mechanical properties and degradation behavior are studied experimentally and theoretically. The composites possess improved strengthening and toughening properties. The bending strength and impact strength of the composites with 40 vol% MAWs are 190 MPa and 150 kJ/m(2), respectively, although PLA has a low viscosity and an average molecular weight of 60,000 g/mol. The mechanical properties of the composites can be further improved by internal structure modification and interface strengthening and a numerical model incorporating the equivalent section method (ESM) is proposed for the bending strength. Micro arc oxidization (MAO) of the MAWs is an effective interfacial strengthening method. The composites exhibit high strength retention during degradation and the PLA in the composite shows a smaller degradation rate than pure PLA. The novel biodegradable composites have large potential in bone fracture fixation under load-bearing conditions.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Biodegradable PLA-based composite; Degradation behaviors; Magnesium alloy wires; Mechanical properties; Strengthening and toughening

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Year:  2015        PMID: 25725562     DOI: 10.1016/j.biomaterials.2015.01.060

Source DB:  PubMed          Journal:  Biomaterials        ISSN: 0142-9612            Impact factor:   12.479


  8 in total

1.  Microstructure-modified biodegradable magnesium alloy for promoting cytocompatibility and wound healing in vitro.

Authors:  Da-Jun Lin; Fei-Yi Hung; Ming-Long Yeh; Truan-Sheng Lui
Journal:  J Mater Sci Mater Med       Date:  2015-09-28       Impact factor: 3.896

2.  Technical feasibility and tissue reaction after silicone-covered biodegradable magnesium stent insertion in the oesophagus: a primary study in vitro and in vivo.

Authors:  Yue-Qi Zhu; Laura Edmonds; Li-Ming Wei; Rei-La Zheng; Ruo-Yu Cheng; Wen-Guo Cui; Ying-Sheng Cheng
Journal:  Eur Radiol       Date:  2016-10-04       Impact factor: 5.315

3.  Preclinical evaluation of acute systemic toxicity of magnesium incorporated poly(lactic-co-glycolic acid) porous scaffolds by three-dimensional printing.

Authors:  Jing Long; Bin Teng; Wei Zhang; Long Li; Ming Zhang; Yingqi Chen; Zhenyu Yao; Xiangbo Meng; Xinluan Wang; Ling Qin; Yuxiao Lai
Journal:  Biomater Transl       Date:  2021-09-28

4.  Silicone-covered biodegradable magnesium-stent insertion in the esophagus: a comparison with plastic stents.

Authors:  Yue-Qi Zhu; Kai Yang; Laura Edmonds; Li-Ming Wei; Reila Zheng; Ruo-Yu Cheng; Wen-Guo Cui; Ying-Sheng Cheng
Journal:  Therap Adv Gastroenterol       Date:  2016-10-13       Impact factor: 4.409

5.  The Degradation Properties of MgO Whiskers/PLLA Composite In Vitro.

Authors:  Yun Zhao; Bei Liu; Hongwei Bi; Jinjun Yang; Wei Li; Hui Liang; Yue Liang; Zhibin Jia; Shuxin Shi; Minfang Chen
Journal:  Int J Mol Sci       Date:  2018-09-13       Impact factor: 5.923

6.  Effects of Magnesium Oxide (MgO) Shapes on In Vitro and In Vivo Degradation Behaviors of PLA/MgO Composites in Long Term.

Authors:  Yun Zhao; Hui Liang; Shiqiang Zhang; Shengwei Qu; Yue Jiang; Minfang Chen
Journal:  Polymers (Basel)       Date:  2020-05-08       Impact factor: 4.329

7.  Fabrication and Characterization of Drug-Loaded Conductive Poly(glycerol sebacate)/Nanoparticle-Based Composite Patch for Myocardial Infarction Applications.

Authors:  Nazanin Zanjanizadeh Ezazi; Rubina Ajdary; Alexandra Correia; Ermei Mäkilä; Jarno Salonen; Marianna Kemell; Jouni Hirvonen; Orlando J Rojas; Heikki J Ruskoaho; Hélder A Santos
Journal:  ACS Appl Mater Interfaces       Date:  2020-02-03       Impact factor: 9.229

8.  Photo-responsive degradable hollow mesoporous organosilica nanoplatforms for drug delivery.

Authors:  Jie Fan; Zhipeng Zhang; Yaru Wang; Shiting Lin; Shun Yang
Journal:  J Nanobiotechnology       Date:  2020-06-15       Impact factor: 10.435

  8 in total

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