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Literature DB >> 25725527

H2S regulation of nitric oxide metabolism.

Gopi K Kolluru¹, Shuai Yuan², Xinggui Shen², Christopher G Kevil³.

Abstract

Nitric oxide (NO) and hydrogen sulfide (H2S) are two major gaseous signaling molecules that regulate diverse physiological functions. Recent publications indicate the regulatory role of H2S on NO metabolism. In this chapter, we discuss the latest findings on H2S-NO interactions through formation of novel chemical derivatives and experimental approaches to study these adducts. This chapter also addresses potential H2S interference on various NO detection techniques, along with precautions for analyzing biological samples from various sources. This information will facilitate critical evaluation and clearer insight into H2S regulation of NO signaling and its influence on various physiological functions.

Entities: CellLine Chemical Disease Gene Species

Keywords: Biochemistry; Nitric oxide synthase; Nitrite; Oxidation; Peroxynitrite; Reduction; Sulfide

Mesh：

Substances：

Year: 2015 PMID： 25725527 PMCID： PMC4413936 DOI： 10.1016/bs.mie.2014.11.040

Source DB: PubMed Journal: Methods Enzymol ISSN： 0076-6879 Impact factor: 1.600

79 in total

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13 in total

1. A new player in bacterial sulfide-inducible transcriptional regulation.

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