Literature DB >> 2572512

The structure of the chicken glutamine synthetase-encoding gene.

H F Pu1, A P Young.   

Abstract

Complementary DNA (cDNA) and genomic clones encoding chicken glutamine synthetase (Glns) have been isolated. The nucleotide (nt) sequence of the 2728-bp cDNA specifies a 91-nt 5' untranslated sequence, a 1119-nt open reading frame, and a 1518-nt 3' untranslated sequence that contains several A + T-rich regions but lacks a canonical endonucleolytic-cleavage/polyadenylation signal. Based on sequence analysis of the cloned gene, the Glns transcription unit spans 7.0 kb and contains seven exons.

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Year:  1989        PMID： 2572512     DOI： 10.1016/0378-1119(89)90348-x

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  8 in total

1.  Steroid hormone receptors activate transcription in glial cells of intact retina but not in primary cultures of retinal glial cells.

Authors:  Y C Li; S Hayes; A P Young
Journal:  J Mol Neurosci       Date:  1997-04       Impact factor: 3.444

2.  The minimal self-sufficient element in a murine G+C-rich promoter is a large element with imperfect dyad symmetry.

Authors:  S L Ackerman; A G Minden; C Y Yeung
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

3.  A transcriptional enhancer of the glutamine synthetase gene that is selective for retinal Müller glial cells.

Authors:  Y C Li; D Beard; S Hayes; A P Young
Journal:  J Mol Neurosci       Date:  1995       Impact factor: 3.444

4.  Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development.

Authors:  S Ben-Or; S Okret
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

5.  Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes.

Authors:  Y Kumada; D R Benson; D Hillemann; T J Hosted; D A Rochefort; C J Thompson; W Wohlleben; Y Tateno
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205

6.  Rapid establishment of high-producing cell lines using dicistronic vectors with glutamine synthetase as the selection marker.

Authors:  H Pu; L M Cashion; P J Kretschmer; Z Liu
Journal:  Mol Biotechnol       Date:  1998-08       Impact factor: 2.695

7.  Advances in animal cell recombinant protein production: GS-NS0 expression system.

Authors:  L M Barnes; C M Bentley; A J Dickson
Journal:  Cytotechnology       Date:  2000-02       Impact factor: 2.058

8.  Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor.

Authors:  A Helmberg; N Auphan; C Caelles; M Karin
Journal:  EMBO J       Date:  1995-02-01       Impact factor: 11.598
  8 in total

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