Literature DB >> 25724967

Fistula-tract Laser Closure (FiLaC™): long-term results and new operative strategies.

P Giamundo1, L Esercizio, M Geraci, L Tibaldi, M Valente.   

Abstract

BACKGROUND: Fistula-tract Laser Closure (FiLaC™) is a sphincter-saving technique for the treatment of anal fistulas that has been shown to be successful in the short and middle term. However, the long-term success rate is unknown. This study aimed to report long-term results in performing FiLaC™.
METHODS: This study was performed as a retrospective observational study. Forty-five patients who underwent FiLaC™ between July 2010 and May 2014 were evaluated. In all cases, FiLaC™ was performed with a diode laser at a wavelength of 1470 nm by means of a radial fiber. Patients and fistula characteristics, previous treatments, healing rates, failures and postoperative incontinence were reviewed.
RESULTS: Median follow-up time was 30 months (range 6-46 months). Thirty-five patients (78%) had a history of previous surgery for their fistulas. Primary healing was observed in 32 patients (71.1%), and the median healing time was 5 weeks (range 3-8 weeks). Eleven of the 13 failures (85%) were early failures (persistent symptoms). No patient reported postoperative incontinence. The best healing rate was observed in patients who had been previously treated with loose seton (19/24, 79%).
CONCLUSIONS: Long-term follow-up after FiLaC™ seems to confirm the favorable short-term success rates reported for this procedure. Although sealing of chronic anal fistulas may be obtained with FiLaC™ in a single treatment, our current strategy consists of placing a loose seton into the fistula tract a few weeks prior to laser treatment. Seton treatment facilitates the following laser procedure and seems to have favorable effects on healing.

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Year:  2015        PMID: 25724967     DOI: 10.1007/s10151-015-1282-9

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN: 1123-6337            Impact factor:   3.781


  14 in total

1.  Sphincter-preserving fistula management: what patients want.

Authors:  C Neal Ellis
Journal:  Dis Colon Rectum       Date:  2010-12       Impact factor: 4.585

2.  Combined partial fistulectomy and electro-cauterization of the intersphincteric tract as a sphincter-sparing treatment of complex anal fistula: clinical and functional outcome.

Authors:  A A Shafik; O El Sibai; I A Shafik
Journal:  Tech Coloproctol       Date:  2014-08-26       Impact factor: 3.781

Review 3.  Anorectal abscess and fistula-in-ano: evidence-based management.

Authors:  Julie A Rizzo; Anna L Naig; Eric K Johnson
Journal:  Surg Clin North Am       Date:  2010-02       Impact factor: 2.741

Review 4.  Fistula-in-ano: advances in treatment.

Authors:  Samer Deeba; Omer Aziz; Parvinder S Sains; Ara Darzi
Journal:  Am J Surg       Date:  2008-05-07       Impact factor: 2.565

5.  Fibrin glue as an adjunct to flap repair of anal fistulas: a randomized, controlled study.

Authors:  C Neal Ellis; Stephen Clark
Journal:  Dis Colon Rectum       Date:  2006-11       Impact factor: 4.585

6.  A randomized, controlled trial of fibrin glue vs. conventional treatment for anal fistula.

Authors:  Ian Lindsey; M M Smilgin-Humphreys; Chris Cunningham; Neil J M Mortensen; Bruce D George
Journal:  Dis Colon Rectum       Date:  2002-12       Impact factor: 4.585

7.  Laser ablation of fistula tract: a sphincter-preserving method for treating fistula-in-ano.

Authors:  Ersin Oztürk; Bariş Gülcü
Journal:  Dis Colon Rectum       Date:  2014-03       Impact factor: 4.585

8.  Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised).

Authors:  Mark H Whiteford; John Kilkenny; Neil Hyman; W Donald Buie; Jeffrey Cohen; Charles Orsay; Gary Dunn; W Brian Perry; C Neal Ellis; Jan Rakinic; Sharon Gregorcyk; Paul Shellito; Richard Nelson; Joe J Tjandra; Graham Newstead
Journal:  Dis Colon Rectum       Date:  2005-07       Impact factor: 4.585

Review 9.  A systematic review of the anal fistula plug for patients with Crohn's and non-Crohn's related fistula-in-ano.

Authors:  J M O'Riordan; I Datta; C Johnston; N N Baxter
Journal:  Dis Colon Rectum       Date:  2012-03       Impact factor: 4.585

Review 10.  Idiopathic fistula-in-ano.

Authors:  Sherief Shawki; Steven D Wexner
Journal:  World J Gastroenterol       Date:  2011-07-28       Impact factor: 5.742

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  26 in total

Review 1.  Short-term efficacy and safety of three novel sphincter-sparing techniques for anal fistulae: a systematic review.

Authors:  S O Adegbola; K Sahnan; G Pellino; P J Tozer; A Hart; R K S Phillips; J Warusavitarne; O D Faiz
Journal:  Tech Coloproctol       Date:  2017-10-29       Impact factor: 3.781

2.  Anal Fistula Laser Closure: the length of fistula is the Achilles' heel.

Authors:  A Lauretta; N Falco; E Stocco; R Bellomo; A Infantino
Journal:  Tech Coloproctol       Date:  2018-12-08       Impact factor: 3.781

3.  The optimal indication for FiLaC® is high trans-sphincteric fistula-in-ano: a prospective cohort of 69 consecutive patients.

Authors:  I Marref; L Spindler; M Aubert; N Lemarchand; N Fathallah; E Pommaret; D Soudan; H Pillant-le Moult; E Safa Far; K Fellous; E Crochet; B Mory; P Benfredj; V de Parades
Journal:  Tech Coloproctol       Date:  2019-09-26       Impact factor: 3.781

4.  Anal fistula closure with FiLaC: new hope or the same old story?

Authors:  D F Altomare
Journal:  Tech Coloproctol       Date:  2015-07-18       Impact factor: 3.781

5.  Does laser fistuloplasty (FiLaC™) offer any benefit over surgical closure of the internal orifice?

Authors:  J Stijns; D K Wasowicz; D D E Zimmerman
Journal:  Tech Coloproctol       Date:  2017-05-22       Impact factor: 3.781

Review 6.  Management of Complex Perineal Fistula Disease.

Authors:  Ricardo Tadayoshi Akiba; Fabio Gontijo Rodrigues; Giovanna da Silva
Journal:  Clin Colon Rectal Surg       Date:  2016-06

Review 7.  Management of Complex Anal Fistulas.

Authors:  Emily J Bubbers; Kyle G Cologne
Journal:  Clin Colon Rectal Surg       Date:  2016-03

Review 8.  Pharmacological Approach to the Management of Crohn's Disease Patients with Perianal Disease.

Authors:  Fernando Bermejo; Iván Guerra; Alicia Algaba; Antonio López-Sanromán
Journal:  Drugs       Date:  2018-01       Impact factor: 9.546

9.  Short-term outcomes of a novel endoscopic clipping device for closure of the internal opening in 100 anorectal fistulas.

Authors:  R L Prosst; A K Joos
Journal:  Tech Coloproctol       Date:  2016-09-26       Impact factor: 3.781

10.  Sphincter-saving therapy for fistula-in-ano: long-term follow-up after FiLaC®.

Authors:  A Wolicki; P Jäger; T Deska; M Senkal
Journal:  Tech Coloproctol       Date:  2020-08-31       Impact factor: 3.781

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