Literature DB >> 25723778

Outcome of robotic surgery for endometrial cancer as a function of patient age.

Xing Ziggy Zeng1, Vincent Lavoue, Susie Lau, Joshua Z Press, Jeremie Abitbol, Raphael Gotlieb, Jeffrey How, Yifan Wang, Walter H Gotlieb.   

Abstract

OBJECTIVE: This study aimed to evaluate and compare robot-assisted surgical staging on clinical outcomes, including quality of life and survival, as a function of patient age.
METHODS: Evaluation and comparison of perioperative morbidity, survival, and postoperative quality of life after prospective accumulation of clinical information including outcome measures for patients with endometrial cancer during the first 5 years of a robotic program, based on the following 3 age categories: women older than 80 years, women between 70 and 80 years, and women younger than 70 years.
RESULTS: All consecutive patients with endometrial cancer undergoing robotic surgery (n = 303) were included, with 197 women younger than 70 years, 75 women between 70 and 80 years, and 31 women older than 80 years. There were significantly more patients with advanced stage (stage II to IV in 17%, 34%, and 35%, P = 0.02) and grade 3 disease (26%, 43%, and 58%, P = 0.002) with increasing age. The perioperative data showed similar grade I or II complications (Clavien-Dindo classification) between the groups, but significantly more grade III and IV complications for women older than 80 years compared with women 80 years or younger (10% vs 1%, P = 0.004). The time needed to resume chore activities was significantly shorter for patients 70 years or older than patients younger than 70 years [8.9 (8.7) vs 18.8 (25.5) days, P = 0.048]. Overall, all patients irrespective of age were highly satisfied with the procedure. There was no difference between young and elderly patients for disease-free survival (P = 0.99).
CONCLUSIONS: Patient's age did not influence minor postoperative morbidity or overall satisfaction after robotic assisted surgery for endometrial cancer. Elderly patients had more major postoperative morbidity but resumed activities quicker than younger patients.

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Year:  2015        PMID: 25723778     DOI: 10.1097/IGC.0000000000000411

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  4 in total

Review 1.  Current and Emerging Prognostic Biomarkers in Endometrial Cancer.

Authors:  Kelechi Njoku; Chloe E Barr; Emma J Crosbie
Journal:  Front Oncol       Date:  2022-04-22       Impact factor: 5.738

Review 2.  Robot-assisted hysterectomy for endometrial and cervical cancers: a systematic review.

Authors:  Immaculate F Nevis; Bahareh Vali; Caroline Higgins; Irfan Dhalla; David Urbach; Marcus Q Bernardini
Journal:  J Robot Surg       Date:  2016-07-16

3.  Lack of improvement in survival rates for women under 50 with endometrial cancer, 2000-2011.

Authors:  Ana M Rodriguez; Kathleen M Schmeler; Yong-Fang Kuo
Journal:  J Cancer Res Clin Oncol       Date:  2015-12-15       Impact factor: 4.553

4.  Sentinel Lymph Node in Aged Endometrial Cancer Patients "The SAGE Study": A Multicenter Experience.

Authors:  Stefano Cianci; Andrea Rosati; Virginia Vargiu; Vito Andrea Capozzi; Giulio Sozzi; Alessandro Gioè; Salvatore Gueli Alletti; Alfredo Ercoli; Francesco Cosentino; Roberto Berretta; Vito Chiantera; Giovanni Scambia; Francesco Fanfani
Journal:  Front Oncol       Date:  2021-10-19       Impact factor: 6.244

  4 in total

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