Literature DB >> 2572257

The effect of age and renal impairment on the pharmacokinetics of xamoterol.

W Bastain1, H F Marlow.   

Abstract

The effects of age and renal function on the pharmacokinetics and plasma concentrations of xamoterol were examined. Peak and steady state concentrations were higher in older patients, but this was due to deterioration of renal function rather than to age itself. The dose of xamoterol only need be reduced in the elderly if there is evidence of impaired renal function.

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Year:  1989        PMID: 2572257      PMCID: PMC1379878          DOI: 10.1111/j.1365-2125.1989.tb03575.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  3 in total

1.  Pharmacokinetics of xamoterol after intravenous and oral administration to patients with chronic heart failure.

Authors:  E V Sorensen; O Faergeman; M Day; W Bastain
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

2.  Pharmacokinetics of xamoterol after intravenous and oral administration to volunteers.

Authors:  W Bastain; M J Boyce; L E Stafford; P B Morton; D A Clarke; H F Marlow
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

3.  The effect of age and cardiac failure on xamoterol pharmacokinetics.

Authors:  A K Scott; J Webster; J C Petrie; W Bastain
Journal:  Br J Clin Pharmacol       Date:  1988-02       Impact factor: 4.335

  3 in total

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