Jing Li1, Miao Zhang1, Lin Chen1, Congbo Cai2, Huijun Sun1, Shuhui Cai3. 1. Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, China. 2. Department of Communication Engineering, Xiamen University, Xiamen, China. Electronic address: cbcai@xmu.edu.cn. 3. Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, China. Electronic address: shcai@xmu.edu.cn.
Abstract
PURPOSE: We employ an amplitude-modulated chirp pulse to selectively excite spins in one or more regions of interest (ROIs) to realize reduced field-of-view (rFOV) imaging based on single-shot spatiotemporally encoded (SPEN) sequence and Fourier transform reconstruction. MATERIALS AND METHODS: The proposed rFOV imaging method was theoretically analyzed and illustrated with numerical simulation and tested with phantom experiments and in vivo rat experiments. In addition, point spread function was applied to demonstrate the feasibility of the proposed method. To evaluate the proposed method, the rFOV results were compared with those obtained using the EPI method with orthogonal RF excitation. RESULTS: The simulation and experimental results show that the proposed method can image one or two separated ROIs along the SPEN dimension in a single shot with higher spatial resolution, less sensitive to field inhomogeneity, and practically no aliasing artifacts. In addition, the proposed method may produce rFOV images with comparable signal-to-noise ratio to the rFOV EPI images. CONCLUSION: The proposed method is promising for the applications under severe susceptibility heterogeneities and for imaging separate ROIs simultaneously.
PURPOSE: We employ an amplitude-modulated chirp pulse to selectively excite spins in one or more regions of interest (ROIs) to realize reduced field-of-view (rFOV) imaging based on single-shot spatiotemporally encoded (SPEN) sequence and Fourier transform reconstruction. MATERIALS AND METHODS: The proposed rFOV imaging method was theoretically analyzed and illustrated with numerical simulation and tested with phantom experiments and in vivo rat experiments. In addition, point spread function was applied to demonstrate the feasibility of the proposed method. To evaluate the proposed method, the rFOV results were compared with those obtained using the EPI method with orthogonal RF excitation. RESULTS: The simulation and experimental results show that the proposed method can image one or two separated ROIs along the SPEN dimension in a single shot with higher spatial resolution, less sensitive to field inhomogeneity, and practically no aliasing artifacts. In addition, the proposed method may produce rFOV images with comparable signal-to-noise ratio to the rFOV EPI images. CONCLUSION: The proposed method is promising for the applications under severe susceptibility heterogeneities and for imaging separate ROIs simultaneously.
Authors: Maxime Yon; João P de Almeida Martins; Qingjia Bao; Matthew D Budde; Lucio Frydman; Daniel Topgaard Journal: NMR Biomed Date: 2020-08-19 Impact factor: 4.044