| Literature DB >> 25721423 |
I-Chuan Yen1, Chen-Wen Yao2, Mao-Tien Kuo3, Chen-Liang Chao4, Chien-Yi Pai2, Wen-Liang Chang5.
Abstract
Three new ubiquinone derivatives, antrocamol LT1, antrocamol LT2, and antrocamol LT3, along with two known compounds, were isolated from Antrodia camphorata (Polyporaceae) mycelium. The structures of these compounds were established on the basis of extensive 1D and 2D NMR spectroscopic analyses. These ubiquinones exhibited selective cytotoxicities against five human cancer cell lines (CT26, A549, HepG2, PC3 and DU-145) with IC50 values ranging from 0.01 to 1.79μΜ.Entities:
Keywords: Antrocamol LT1; Antrocamol LT2; Antrocamol LT3; Antrodia camphorata; Cytotoxicity; Ubiquinone derivative
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Year: 2015 PMID： 25721423 DOI： 10.1016/j.fitote.2015.02.010
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882