Literature DB >> 25720517

Bariatric Surgery Patients' Response to a Chronic Pain Rehabilitation Program.

Anilga Tabibian1, Karen B Grothe, Manpreet S Mundi, Todd A Kellogg, Matthew M Clark, Cynthia O Townsend.   

Abstract

BACKGROUND: Chronic pain (CP) is a prevalent and disabling diagnosis in obese individuals, but how bariatric surgery patients respond to chronic pain rehabilitation treatment programs has not previously been described.
OBJECTIVES: The aim of this study was to compare treatment outcomes of a chronic pain rehabilitation program (psychological and pain variables, medication use, treatment completion rates) for post-bariatric surgery patients to those of a non-bariatric surgery control group.
SETTING: Three week outpatient multidisciplinary chronic pain program in an academic medical center.
METHODS: This was a retrospective case-control study. Medical records of patients admitted to the Pain Rehabilitation Center at Mayo Clinic from 2008 to 2012 were reviewed. One hundred six patients with a history of bariatric surgery (cases) were identified and matched to 106 patients without a history of bariatric surgery (controls) on age, gender, and smoking status (n = 202). Matched t tests and McNemar's tests were used for analyses.
RESULTS: Mean age was 46 years; 91% were female and 58% were non-smokers. The majority of cases (71%) had undergone Roux-en-Y gastric bypass. Bariatric patients had higher rates of benzodiazepine use at discharge (33 vs. 19%, p = 0.0433) and were less likely to complete treatment (87 vs. 97%, p = 0.007) compared to controls. Morphine equivalent use for cases was 127.3 mg ± 135.4 (n = 62) compared to 88.3 mg ± 95.3 (n = 62), p = 0.12, for controls at admission.
CONCLUSIONS: These results suggest that bariatric patients may be at risk for treatment non-adherence and have difficulty reducing medication use in the treatment of chronic pain.

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Year:  2015        PMID: 25720517     DOI: 10.1007/s11695-015-1634-6

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


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Authors:  Cynthia O Townsend; Jennifer L Kerkvliet; Barbara K Bruce; Jeffrey D Rome; Michael W Hooten; Connie A Luedtke; John E Hodgson
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3.  Obesity and pain are associated in the United States.

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Journal:  Obesity (Silver Spring)       Date:  2012-01-19       Impact factor: 5.002

4.  Pharmacokinetic modeling of M6G formation after oral administration of morphine in healthy volunteers.

Authors:  J Lötsch; M Weiss; G Ahne; G Kobal; G Geisslinger
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5.  Alcohol consumption and alcohol problems after bariatric surgery in the Swedish obese subjects study.

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6.  Characteristics of the gastrointestinal absorption of morphine in rats.

Authors:  T Tan; M Kuramoto; T Takahashi; H Nakamura; Y Nakanishi; Y Imasato; H Yoshimura
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7.  Metabolic/bariatric surgery worldwide 2011.

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8.  Blood alcohol concentrations rise rapidly and dramatically after Roux-en-Y gastric bypass.

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9.  Musculoskeletal pain in the obese: a comparison with a general population and long-term changes after conventional and surgical obesity treatment.

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Review 10.  Pharmacology of morphine in obese patients: clinical implications.

Authors:  Célia Lloret Linares; Xavier Declèves; Jean Michel Oppert; Arnaud Basdevant; Karine Clement; Christophe Bardin; Jean Michel Scherrmann; Jean Pierre Lepine; Jean François Bergmann; Stéphane Mouly
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  2 in total

1.  Effects of Neighborhood Walkability on Physical Activity and Sedentary Behavior Long-Term Post-Bariatric Surgery.

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Journal:  Obes Surg       Date:  2017-06       Impact factor: 4.129

2.  Increased intravenous morphine self-administration following Roux-en-Y gastric bypass in dietary obese rats.

Authors:  Jessica M Biegler; Christopher S Freet; Nelli Horvath; Ann M Rogers; Andras Hajnal
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