Literature DB >> 25719568

Synthesis of pyrazoles from 1,3-diols via hydrogen transfer catalysis.

Daniel C Schmitt1, Alexandria P Taylor1, Andrew C Flick1, Robert E Kyne1.   

Abstract

1,3-Diols engage in ruthenium-catalyzed hydrogen transfer in the presence of alkyl hydrazines to provide 1,4-disubstituted pyrazoles. Regioselective synthesis of unsymmetrical pyrazoles from β-hydroxy ketones is also described.

Entities:  

Year:  2015        PMID： 25719568     DOI： 10.1021/acs.orglett.5b00266

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Direct Synthesis of Symmetrical Azines from Alcohols and Hydrazine Catalyzed by a Ruthenium Pincer Complex: Effect of Hydrogen Bonding.

Authors:  Jonathan O Bauer; Gregory Leitus; Yehoshoa Ben-David; David Milstein
Journal:  ACS Catal       Date:  2016-11-17       Impact factor: 13.084

Review 2.  Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer's Disease and Parkinson's Disease Treatment (2011-2020).

Authors:  Xuefei Li; Yanbo Yu; Zhude Tu
Journal:  Molecules       Date:  2021-02-24       Impact factor: 4.411

3.  Monoallylation and benzylation of dicarbonyl compounds with alcohols catalysed by a cationic cobalt(iii) compound.

Authors:  Mohan Chandra Sau; Smita Mandal; Manish Bhattacharjee
Journal:  RSC Adv       Date:  2021-03-01       Impact factor: 3.361

4.  Continuous-flow synthesis of 3,5-disubstituted pyrazoles via sequential alkyne homocoupling and Cope-type hydroamination.

Authors:  Sándor B Ötvös; Ádám Georgiádes; Dániel Ozsvár; Ferenc Fülöp
Journal:  RSC Adv       Date:  2019-03-13       Impact factor: 4.036
  4 in total

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