Literature DB >> 25719225

A new biomimetic route to engineer enzymatically active mechano-responsive materials.

César Rios1, Johan Longo, Sarah Zahouani, Tony Garnier, Cédric Vogt, Andreas Reisch, Bernard Senger, Fouzia Boulmedais, Joseph Hemmerlé, Karim Benmlih, Benoît Frisch, Pierre Schaaf, Loïc Jierry, Philippe Lavalle.   

Abstract

Using modified β-galactosidase covalently linked to cross-linked polyelectrolyte multilayers (PEM), catalytically active materials have been designed. Their enzymatic activity can be modulated, partially in a reversible way, simply by stretching. This strategy, based on enzyme conformational changes, constitutes a new tool for the development of biocatalytic mechano-responsive materials.

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Year:  2015        PMID: 25719225     DOI: 10.1039/c5cc00329f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

Review 1.  Towards nanomedicines of the future: Remote magneto-mechanical actuation of nanomedicines by alternating magnetic fields.

Authors:  Yuri I Golovin; Sergey L Gribanovsky; Dmitry Y Golovin; Natalia L Klyachko; Alexander G Majouga; Аlyssa M Master; Marina Sokolsky; Alexander V Kabanov
Journal:  J Control Release       Date:  2015-09-25       Impact factor: 9.776

2.  Manual control of catalytic reactions: Reactions by an apoenzyme gel and a cofactor gel.

Authors:  Yuichiro Kobayashi; Yoshinori Takashima; Akihito Hashidzume; Hiroyasu Yamaguchi; Akira Harada
Journal:  Sci Rep       Date:  2015-11-05       Impact factor: 4.379

  2 in total

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