| Literature DB >> 2571742 |
T Harrer1, K Messing, U Bienzle, E Meyer, J Giedl, J R Kalden.
Abstract
26 homosexual men with HIV-infection and lymphadenopathy syndrome were examined between 1982 and 1984 and prospectively observed over a period of 58 months (median, range 53-69 months). 16 (61.5%) developed full blown AIDS within a median period of 41 months (23-63 months). 12 of them died 50 months (median, range 29-67 months) after the first examination. 10 patients showed no symptoms of AIDS after a median observation time of 57 months (54-63 months). A panel of clinical symptoms, signs of concomitant infections, chemical and immunological analyses, including a lymphnode biopsy were correlated to the course of the disease. A decreased proportion of CD4-cells and a lower CD4/CD8 ratio in the lymphnode suspensions at the first examination in patients with disease progression were the only parameter which correlated significantly with the development of AIDS.Entities:
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Year: 1989 PMID: 2571742 DOI: 10.1007/BF01721419
Source DB: PubMed Journal: Klin Wochenschr ISSN: 0023-2173