Literature DB >> 2571742

[Manifestation of AIDS in HIV infected homosexual males with lymphadenopathy syndrome].

T Harrer1, K Messing, U Bienzle, E Meyer, J Giedl, J R Kalden.   

Abstract

26 homosexual men with HIV-infection and lymphadenopathy syndrome were examined between 1982 and 1984 and prospectively observed over a period of 58 months (median, range 53-69 months). 16 (61.5%) developed full blown AIDS within a median period of 41 months (23-63 months). 12 of them died 50 months (median, range 29-67 months) after the first examination. 10 patients showed no symptoms of AIDS after a median observation time of 57 months (54-63 months). A panel of clinical symptoms, signs of concomitant infections, chemical and immunological analyses, including a lymphnode biopsy were correlated to the course of the disease. A decreased proportion of CD4-cells and a lower CD4/CD8 ratio in the lymphnode suspensions at the first examination in patients with disease progression were the only parameter which correlated significantly with the development of AIDS.

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Year:  1989        PMID: 2571742     DOI: 10.1007/BF01721419

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  3 in total

1.  The prognostic value of histopathology in persistent generalized lymphadenopathy in homosexual men.

Authors:  R Fernandez; J Mouradian; C Metroka; J Davis
Journal:  N Engl J Med       Date:  1983-07-21       Impact factor: 91.245

2.  Follow-up at 41/2 years on homosexual men with generalized lymphadenopathy.

Authors:  U Mathur-Wagh; D Mildvan; R T Senie
Journal:  N Engl J Med       Date:  1985-12-12       Impact factor: 91.245

3.  [Follow-up in HIV-infected homosexual males with lymphadenopathy syndrome].

Authors:  T Harrer; K Messing; U Bienzle; E Meyer; J Giedl; J R Kalden
Journal:  Klin Wochenschr       Date:  1987-09-15
  3 in total
  1 in total

1.  Intralymphatic interleukin-2 in combination with zidovudine for the therapy of patients with AIDS.

Authors:  T Harrer; J Schwab; W G Struff; M Schmitt; J H Ficker; W Rödl; H Parsch; J R Kalden; M Gramatzki
Journal:  Infection       Date:  1998 Nov-Dec       Impact factor: 3.553

  1 in total

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