| Literature DB >> 25717354 |
Sven Möbius-Winkler1, Nicolas Majunke1, Marcus Sandri1, Norman Mangner1, Axel Linke1, Gregg W Stone1, Ingo Dähnert1, Gerhard Schuler1, Peter B Sick1.
Abstract
Transcatheter closure of the left atrial appendage has been developed as an alternative to chronic oral anticoagulation for stroke prevention in patients with atrial fibrillation, and as a primary therapy for patients with contraindications to chronic oral anticoagulation. The promise of this new intervention compared with warfarin has been supported by several, small studies and two pivotal randomized trial with the Watchman Device. The results regarding risk reduction for stroke have been favourable although acute complications were not infrequent. Procedural complications, which are mainly related to transseptal puncture and device implantation, include air embolism, pericardial effusions/tamponade and device embolization. Knowledge of nature, management and prevention of complications should minimize the risk of complications and allow transcatheter left atrial appendage closure to emerge as a therapeutic option for patients with atrial fibrillation at risk for cardioembolic stroke.Entities:
Keywords: Atrial fibrillation; Complications; Left atrial appendage; Stroke prevention; WATCHMAN® device
Year: 2015 PMID: 25717354 PMCID: PMC4325303 DOI: 10.4330/wjc.v7.i2.65
Source DB: PubMed Journal: World J Cardiol