Literature DB >> 25717248

Determination of surgical priorities in appendicitis based on the probability of undetected appendiceal perforation.

Sang Chul Lee1, Geon Park1, Byung-Jo Choi1, Say-June Kim1.   

Abstract

AIM: To identify risk factors of actual appendiceal perforation when computed tomography (CT) scans suggest nonperforated appendicitis and accordingly determine surgical priority.
METHODS: We collected database of 1362 patients who underwent an appendectomy for acute appendicitis between 2006 and 2013. A single radiologist selected 1236 patients whose CT scans were suggestive of nonperforated appendicitis. Patients were divided into 2 groups: actual nonperforation group and actual perforation group according to intraoperative and pathologic features. Comparison of the 2 groups were made using binary logistic regression.
RESULTS: Of 1236 patients, 90 (7.3%) were found to have actual appendiceal perforation. Four risk factors related with actual appendiceal perforation were identified: body temperature≥37.6  °C (HR=1.912, 95%CI: 1.161-3.149; P=0.011), out-of-hospital symptom duration≥72 h (HR=2.454, 95%CI: 1.292-4.662; P=0.006), age≥35 years (HR=3.358, 95%CI: 1.968-5.728; P<0.001), and appendiceal diameter on CT scan≥8 mm (HR=4.294, 95%CI: 1.034-17.832; P=0.045). Actual appendiceal perforation group showed longer operation time, later initiation of diet, longer use of parenteral narcotics, longer hospital stay, and higher incidence of postoperative complications (P<0.05).
CONCLUSION: We proposed here new criteria to select patients with adverse clinical outcomes after appendectomy among the patients with radiologically nonperforated appendicitis. Surgical appendectomy outcomes could be improved by determining the surgical priority according to our criteria.

Entities:  

Keywords:  Appendiceal perforation; Appendicitis; Operative priority; Practice guideline; Prognosis

Mesh:

Year:  2015        PMID: 25717248      PMCID: PMC4326150          DOI: 10.3748/wjg.v21.i7.2131

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  20 in total

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2.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

Authors:  M E Charlson; P Pompei; K L Ales; C R MacKenzie
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3.  How time affects the risk of rupture in appendicitis.

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4.  Appendicitis: why so complicated? Analysis of 5755 consecutive appendectomies.

Authors:  V A Pittman-Waller; J G Myers; R M Stewart; D L Dent; C P Page; G A Gray; B A Pruitt; H D Root
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5.  Perforated appendicitis: is early laparoscopic appendectomy appropriate?

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6.  An evidence-based definition for perforated appendicitis derived from a prospective randomized trial.

Authors:  Shawn D St Peter; Susan W Sharp; George W Holcomb; Daniel J Ostlie
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7.  The natural history of appendicitis in adults. A prospective study.

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8.  Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment Program.

Authors:  Joseph Cuschieri; Michael Florence; David R Flum; Gregory J Jurkovich; Paul Lin; Scott R Steele; Rebecca Gaston Symons; Richard Thirlby
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9.  Delayed versus immediate surgery in acute appendicitis: do we need to operate during the night?

Authors:  Dani Yardeni; Ronald B Hirschl; Robert A Drongowski; Daniel H Teitelbaum; James D Geiger; Arnold G Coran
Journal:  J Pediatr Surg       Date:  2004-03       Impact factor: 2.545

10.  Accuracy of computed tomography in predicting appendiceal perforation.

Authors:  Jason D Fraser; Pablo Aguayo; Susan W Sharp; Charles L Snyder; Douglas C Rivard; Brent E Cully; Ronald J Sharp; Daniel J Ostlie; Shawn D St Peter
Journal:  J Pediatr Surg       Date:  2010-01       Impact factor: 2.545

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