Antoine Vanier1, Alain Leplège2, Jean-Benoit Hardouin3, Véronique Sébille3, Bruno Falissard4. 1. U669 PSIGIAM, INSERM, 97 Boulevard de Port Royal, 75679 Paris Cedex 14, France; EA4275 "Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences", University of Nantes, 1 rue Gaston Veil, 44035 Nantes Cedex 1, France; Department of Biostatistics, UPMC Univ. Paris 06, 91 Boulevard de l'hôpital, 75013, Paris, France; Department of Biostatistics Public Health and Medical Informatics, AP-HP University Hospitals Pitié-Salpêtrière Charles-Foix, 47-83 Boulevard de l'hôpital, 75651 Paris Cedex 13, France. Electronic address: antoine.vanier@psl.aphp.fr. 2. Department of History and Philosophy of Sciences, Sorbonne Paris Cité, Université Paris Diderot, 4 rue Elsa Morante, 75205 Paris Cedex 13, France. 3. EA4275 "Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences", University of Nantes, 1 rue Gaston Veil, 44035 Nantes Cedex 1, France. 4. U669 PSIGIAM, INSERM, 97 Boulevard de Port Royal, 75679 Paris Cedex 14, France; Université Paris-Sud and Université Paris-Descartes, 63, rue Gabriel Péri, 94276 Le Kremlin-Bicêtre Cedex, France; Department of Public Health, APHP University Hospitals Paris-Sud, 78 Rue de la Division du Général Leclerc, 94270 Le Kremlin-Bicêtre, France.
Abstract
OBJECTIVES: The purpose of randomized control trials (RCTs) can be the assessment of the direct effect of treatment on health-related quality of life (HRQL). Response shift (RS) theory considers that a change in HRQL scores observed over time cannot be explained solely by a direct effect of a medical condition, it may also result from a change in the way people appraise their HRQL. The RS effect is a potential bias that is liable to compromise efficient assessment of the effect of treatment on HRQL. STUDY DESIGN AND SETTING: We hypothesize a link between the RS effect on HRQL scores and the level of complexity of HRQL conceptualization. RESULTS: We discuss how the impact of reconceptualization on scores depends on the complexity of the linguistic definition of a subjective construct and how for reprioritization the impact depends on the dimensionality. The linguistic theory of semantic primes is used to help identify how subjective constructs can be classified according to the complexity of their definitions. CONCLUSION: Finally, we suggest that the impact of the RS effect on HRQL scores could be avoided (or lessened) if questionnaires were designed with a rule of "the least semantic and psychometric complexity" in mind.
OBJECTIVES: The purpose of randomized control trials (RCTs) can be the assessment of the direct effect of treatment on health-related quality of life (HRQL). Response shift (RS) theory considers that a change in HRQL scores observed over time cannot be explained solely by a direct effect of a medical condition, it may also result from a change in the way people appraise their HRQL. The RS effect is a potential bias that is liable to compromise efficient assessment of the effect of treatment on HRQL. STUDY DESIGN AND SETTING: We hypothesize a link between the RS effect on HRQL scores and the level of complexity of HRQL conceptualization. RESULTS: We discuss how the impact of reconceptualization on scores depends on the complexity of the linguistic definition of a subjective construct and how for reprioritization the impact depends on the dimensionality. The linguistic theory of semantic primes is used to help identify how subjective constructs can be classified according to the complexity of their definitions. CONCLUSION: Finally, we suggest that the impact of the RS effect on HRQL scores could be avoided (or lessened) if questionnaires were designed with a rule of "the least semantic and psychometric complexity" in mind.
Authors: Carolyn E Schwartz; Gudrun Rohde; Elijah Biletch; Richard B B Stuart; I-Chan Huang; Joseph Lipscomb; Roland B Stark; Richard L Skolasky Journal: Qual Life Res Date: 2021-10-27 Impact factor: 4.147
Authors: Ingrid V E Carlier; Wessel A van Eeden; Kim de Jong; Erik J Giltay; Martijn S van Noorden; Christina van der Feltz-Cornelis; Frans G Zitman; Henk Kelderman; Albert M van Hemert Journal: Int J Methods Psychiatr Res Date: 2019-06-17 Impact factor: 4.035
Authors: Antoine Vanier; Frans J Oort; Leah McClimans; Nikki Ow; Bernice G Gulek; Jan R Böhnke; Mirjam Sprangers; Véronique Sébille; Nancy Mayo Journal: Qual Life Res Date: 2021-04-28 Impact factor: 4.147