Literature DB >> 2571559

Different haplotypes for cystic fibrosis-linked DNA polymorphisms in Polish and Dutch populations.

D Maciejko1, J Bal, T Mazurczak, G te Meerman, C Buys, B Oostra, D Halley.   

Abstract

We analyzed DNA from 34 Polish and 63 Dutch cystic fibrosis (CF) patients and their families using the polymorphic markers XV2c and KM19, which are in linkage disequilibrium with the CF mutation. Strong linkage disequilibrium was found in the Dutch population sample, but the haplotypes of the Polish chromosomes showed a significantly less extreme disequilibrium. Our data and previous studies indicate that the highest degree of homogeneity of the CF defect and hence the best possible use of the XV2c/KM19/CF linkage disequilibrium for CF carrier detection/exclusion is in populations of northern European origin.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2571559     DOI： 10.1007/BF00285159

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7.

Authors:  R G Knowlton; O Cohen-Haguenauer; N Van Cong; J Frézal; V A Brown; D Barker; J C Braman; J W Schumm; L C Tsui; M Buchwald
Journal:  Nature       Date:  1985 Nov 28-Dec 4       Impact factor: 49.962

2.  Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study.

Authors:  A Beaudet; A Bowcock; M Buchwald; L Cavalli-Sforza; M Farrall; M C King; K Klinger; J M Lalouel; G Lathrop; S Naylor
Journal:  Am J Hum Genet       Date:  1986-12       Impact factor: 11.025

3.  Localization of DNA probes with tight linkage to the cystic fibrosis locus by in situ hybridization using fibroblasts with a 7q22 deletion.

Authors:  A H van der Hout; A Y van der Veen; J A Aten; C H Buys
Journal:  Hum Genet       Date:  1988-10       Impact factor: 4.132

4.  Isolation of a further anonymous informative DNA sequence from chromosome seven closely linked to cystic fibrosis.

Authors:  P J Scambler; B J Wainwright; E Watson; G Bates; G Bell; R Williamson; M Farrall
Journal:  Nucleic Acids Res       Date:  1986-03-11       Impact factor: 16.971

5.  Patterns of polymorphism and linkage disequilibrium for cystic fibrosis.

Authors:  X Estivill; P J Scambler; B J Wainwright; K Hawley; P Frederick; M Schwartz; M Baiget; J Kere; R Williamson; M Farrall
Journal:  Genomics       Date:  1987-11       Impact factor: 5.736

6.  A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands.

Authors:  X Estivill; M Farrall; P J Scambler; G M Bell; K M Hawley; N J Lench; G P Bates; H C Kruyer; P A Frederick; P Stanier
Journal:  Nature       Date:  1987 Apr 30-May 6       Impact factor: 49.962

7.  Three additional DNA polymorphisms in the met gene and D7S8 locus: use in prenatal diagnosis of cystic fibrosis.

Authors:  M Dean; P O'Connell; M Leppert; M Park; J A Amos; D G Phillips; R White; G F Vande Woude
Journal:  J Pediatr       Date:  1987-10       Impact factor: 4.406

8.  Linkage relationships and allelic associations of the cystic fibrosis locus and four marker loci.

Authors:  J Schmidtke; M Krawczak; M Schwartz; M Alkan; M Bonduelle; E Bühler; M Chemke; T Darnedde; J Domagk; W Engel
Journal:  Hum Genet       Date:  1987-08       Impact factor: 4.132

9.  A closely linked genetic marker for cystic fibrosis.

Authors:  R White; S Woodward; M Leppert; P O'Connell; M Hoff; J Herbst; J M Lalouel; M Dean; G Vande Woude
Journal:  Nature       Date:  1985 Nov 28-Dec 4       Impact factor: 49.962

10.  Localization of cystic fibrosis locus to human chromosome 7cen-q22.

Authors:  B J Wainwright; P J Scambler; J Schmidtke; E A Watson; H Y Law; M Farrall; H J Cooke; H Eiberg; R Williamson
Journal:  Nature       Date:  1985 Nov 28-Dec 4       Impact factor: 49.962
View more
  3 in total

1.  Gradient of distribution in Europe of the major CF mutation and of its associated haplotype. European Working Group on CF Genetics (EWGCFG).

Authors: 
Journal:  Hum Genet       Date:  1990-09       Impact factor: 4.132

2.  Frequency of the cystic fibrosis mutation delta F508 in Poland.

Authors:  J Bal; D Maciejko; T Mazurczak; A Potocka; M Krawczak; J Reiss
Journal:  Hum Genet       Date:  1991-01       Impact factor: 4.132

Review 3.  The cystic fibrosis defect approached from different angles--new perspectives on the gene, the chloride channel, diagnosis and therapy.

Authors:  D J Halley; J Bijman; H R de Jonge; M Sinaasappel; H J Neijens; M F Niermeijer
Journal:  Eur J Pediatr       Date:  1990-07       Impact factor: 3.183
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.