| Literature DB >> 25711906 |
Abstract
Fast varying 3-O-sulfated groups in epithelial KIT+ progenitors provides a cellular mechanism to respond to FGFR2b-mediated signaling and expansion of fetal and adult progenitors. This is allowed by the synthesis of 3-O-sulfated heparan sulfate that up-regulate KIT and 3-O-sulfotransferase enzymes, augmenting 3-O-sulfated heparan sulfate.Entities:
Year: 2015 PMID: 25711906 PMCID: PMC4414833 DOI: 10.1007/s12079-015-0277-7
Source DB: PubMed Journal: J Cell Commun Signal ISSN: 1873-9601 Impact factor: 5.782