Literature DB >> 25711906

Heparan sulfate provides a mechanism to respond to FGFR2b and control regenerative expansion.

Enrique Brandan1.   

Abstract

Fast varying 3-O-sulfated groups in epithelial KIT+ progenitors provides a cellular mechanism to respond to FGFR2b-mediated signaling and expansion of fetal and adult progenitors. This is allowed by the synthesis of 3-O-sulfated heparan sulfate that up-regulate KIT and 3-O-sulfotransferase enzymes, augmenting 3-O-sulfated heparan sulfate.

Entities:  

Year:  2015        PMID: 25711906      PMCID: PMC4414833          DOI: 10.1007/s12079-015-0277-7

Source DB:  PubMed          Journal:  J Cell Commun Signal        ISSN: 1873-9601            Impact factor:   5.782


  1 in total

1.  Hs3st3-modified heparan sulfate controls KIT+ progenitor expansion by regulating 3-O-sulfotransferases.

Authors:  Vaishali N Patel; Isabelle M A Lombaert; Samuel N Cowherd; Nicholas W Shworak; Yongmei Xu; Jian Liu; Matthew P Hoffman
Journal:  Dev Cell       Date:  2014-06-23       Impact factor: 12.270

  1 in total
  1 in total

1.  Erratum to: Pick of the Year 2014.

Authors:  Bernard Perbal
Journal:  J Cell Commun Signal       Date:  2015-09       Impact factor: 5.782

  1 in total

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