Literature DB >> 2570739

Effects of bestatin on intrauterine growth of rat fetuses.

M Furuhashi1, S Mizutani, O Kurauchi, M Kasugai, Y Tomoda.   

Abstract

Pregnant Wistar rats were injected with bestatin, a specific inhibitor of aminopeptidase M. Placental aminopeptidase M activity was inhibited by injection of bestatin, and fetal body weight was statistically lower than that in the saline-injected or control group. Our present data suggest that placental aminopeptidase M plays an important role in fetal growth.

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Year:  1989        PMID: 2570739     DOI: 10.1055/s-2007-1009239

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN: 0018-5043            Impact factor:   2.936


  2 in total

Review 1.  Placental leucine aminopeptidase- and aminopeptidase A- deficient mice offer insight concerning the mechanisms underlying preterm labor and preeclampsia.

Authors:  Shigehiko Mizutani; John W Wright; Hiroshi Kobayashi
Journal:  J Biomed Biotechnol       Date:  2010-12-06

Review 2.  Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.

Authors:  Brigitte Bauvois; Daniel Dauzonne
Journal:  Med Res Rev       Date:  2006-01       Impact factor: 12.944

  2 in total

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