Kok-Yoon Chee1, Adarsh Tripathi2, Ajit Avasthi3, Mian-Yoon Chong4, Kang Sim5, Shu-Yu Yang6, Sandeep Glover3, Yu-Tao Xiang7, Tian-Mei Si8, Shigenobu Kanba9, Yan-Ling He10, Min-Soo Lee11, Helen Fung-Kum Chiu12, Hironori Kuga9, Rathi Mahendran13, Pichet Udormatn14, Roy A Kallivayalil15, Andi J Tanra16, Margarita Maramis17, Naotaka Shinfuku18, Winston W Shen19, Chay-Hoon Tan20, Norman Sartorius21. 1. Department of Psychiatry & Mental Health, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia. 2. Department of Psychiatry, King George's Medical University, Chowk, Lucknow, India. 3. Department of Psychiatry, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. 4. Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital-Kaohsiung Medical Center and School of Medicine, Chang Gung University, Taiwan, China. 5. Institute of Mental Health, Buangkok View, Buangkok Green Medical Park Singapore, Taipei, Taiwan, China. 6. Department of Pharmacy, Taipei City Hospital, Taipei, Taiwan, China. 7. Faculty of Health Sciences, University of Macau, Macao SAR, China. 8. Department of Psychiatry, Peking University Institute of Mental Health, Beijing, China. 9. Department of Neuropsychiatry, Kyushu University, Fukuoka, Japan. 10. Department of Psychiatric Epidemiology, Shanghai Mental Health Center, Shanghai, China. 11. Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea. 12. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, China. 13. Department of Psychological Medicine, National University Hospital, Singapore. 14. Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand. 15. Department of Psychiatry, Pushpagiri Medical College, Thiruvalla, India. 16. Department of Psychiatry, Hasanuddin University Faculty of Medicine, Makassar, Sulawesi Selatan, Indonesia. 17. Dr. Soetomo Hospital - Faculty of Medicine, Airlangga University, Jawa Timur, Indonesia. 18. Department of Psychiatry, Kobe University, Kobe, Japan. 19. Department of Psychiatry, TMU-Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan. 20. Department of Pharmacology, National University of Singapore, Singapore. 21. Association for the Improvement of Mental Health Programmes, Geneva, Switzerland.
Abstract
INTRODUCTION: Research in prescription pattern of antidepressants in Asia is lacking. This study aims to compare the antidepressants prescription pattern in Asia in 2003-2004 and 2013. METHODS: The Research in East Asia Psychotropic Prescription Pattern on Antidepressants (REAP-AD) had worked collaboratively in 2003-2004 (REAP-AD 2003/2004) and 2013 (REAP-AD 2013) to study the prescription pattern of antidepressants in Asia. The REAP-AD 2013 study was conducted in China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand using a unified research protocol and questionnaire. RESULTS: Forty psychiatric centers participated in REAP-AD 2013 and a total of 2,319 patients receive antidepressants were analyzed. In 2013, 39.6% of the antidepressant prescriptions were for diagnoses other thandepressive disorder compared with 38.4% in REAP-AD 2003/2004. Out of all the antidepressants listed in the Anatomical Therapeutic Chemical Classification index by the World Health Organization Collaborating Center for Drug Statistics Methodology (Oslo), only 38% antidepressants were prescribed in participating centers in 2013 compared with 46% in REAP-AD 2003/2004. The selective serotonin reuptake inhibitors were the most common antidepressant prescribed in the participating centers, which was similar to the 2003-2004 survey. Prescription of newer generation antidepressants had increased in 2013 survey; on the contrary, prescription of tricyclic antidepressants had reduced. DISCUSSION: This study has contributed significantly in relation to the changing patterns of antidepressant use in all the participating Asian centers in the last 10 years. The findings are important in shaping optimal antidepressant prescription and future policy making.
INTRODUCTION: Research in prescription pattern of antidepressants in Asia is lacking. This study aims to compare the antidepressants prescription pattern in Asia in 2003-2004 and 2013. METHODS: The Research in East Asia Psychotropic Prescription Pattern on Antidepressants (REAP-AD) had worked collaboratively in 2003-2004 (REAP-AD 2003/2004) and 2013 (REAP-AD 2013) to study the prescription pattern of antidepressants in Asia. The REAP-AD 2013 study was conducted in China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand using a unified research protocol and questionnaire. RESULTS: Forty psychiatric centers participated in REAP-AD 2013 and a total of 2,319 patients receive antidepressants were analyzed. In 2013, 39.6% of the antidepressant prescriptions were for diagnoses other thandepressive disorder compared with 38.4% in REAP-AD 2003/2004. Out of all the antidepressants listed in the Anatomical Therapeutic Chemical Classification index by the World Health Organization Collaborating Center for Drug Statistics Methodology (Oslo), only 38% antidepressants were prescribed in participating centers in 2013 compared with 46% in REAP-AD 2003/2004. The selective serotonin reuptake inhibitors were the most common antidepressant prescribed in the participating centers, which was similar to the 2003-2004 survey. Prescription of newer generation antidepressants had increased in 2013 survey; on the contrary, prescription of tricyclic antidepressants had reduced. DISCUSSION: This study has contributed significantly in relation to the changing patterns of antidepressant use in all the participating Asian centers in the last 10 years. The findings are important in shaping optimal antidepressant prescription and future policy making.
Authors: Robyn Tamblyn; David Westfall Bates; David L Buckeridge; Will Dixon; Alan J Forster; Nadyne Girard; Jennifer Haas; Bettina Habib; Siyana Kurteva; Jack Li; Therese Sheppard Journal: BMJ Open Date: 2019-05-14 Impact factor: 2.692
Authors: Sharmila V Jalgaonkar; Tausif I Mapara; Urwashi I Parmar; Mahesh L Patil; Shilpa Adarkar; Shubhangi Parkar Journal: Perspect Clin Res Date: 2020-05-07