Literature DB >> 2570591

Antigen processing: current issues, exceptional cases (Thy 1 alloantigen, MHC class-II-restricted cytolytic T cells), and implications for vaccine development.

B M Chain1, N A Mitchison, T J Mitchison, D H Davies, J Marcinkiewicz.   

Abstract

A dogmatic view of antigen processing is presented in outline, followed by a survey of unresolved issues in the subject. The activity of Thy 1 as an alloantigen, and allospecific MHC Class-II-restricted cytolytic T cells offer examples of exceptional cases of antigen presentation. Implications for the design of vaccines are drawn.

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Year:  1989        PMID： 2570591     DOI： 10.1016/0896-8411(89)90116-9

Source DB:  PubMed          Journal:  J Autoimmun        ISSN： 0896-8411            Impact factor:   7.094


  1 in total

1.  Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Authors:  Véronique Schulten; Jason A Greenbaum; Michael Hauser; Denise M McKinney; John Sidney; Ravi Kolla; Cecilia S Lindestam Arlehamn; Carla Oseroff; Rapheul Alam; David H Broide; Fatima Ferreira; Fatima Ferreira-Briza; Howard M Grey; Alessandro Sette; Bjoern Peters
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-11       Impact factor: 11.205
  1 in total

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