Grace J Lee1, Ashley R Curiel2, Karen J Miller3, Stacy Amano4, Richard Gorsuch4, Gary W Small3. 1. Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, CA 90024, USA. 2. Pepperdine University, Los Angeles, CA 90045, USA. 3. Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, CA 90024, USA ; Longevity Center Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90024, USA. 4. Fuller Theological Seminary, Pasadena, CA, USA.
Abstract
AIMS: In the current study, we explored the potential effects of hormone therapy (HT) on language functioning in healthy, postmenopausal women and compared them with men of similar ages. MATERIALS & METHODS: Language functioning on tasks of verbal fluency and object naming was examined in 100 participants (mean age: 61.9 years; 33 HT users, 15 HT non-users and 52 men) at baseline and follow-up (mean follow-up time period: 2.6 years). RESULTS: At baseline, men had higher composite language scores than HT users. However, HT users demonstrated more improvement over time compared with men, whereas HT non-users performed similarly to men, with no improvement over time. Longer duration of HT use was not associated with improved performance on language tests. CONCLUSION: These results suggest an association between HT use and better language ability in postmenopausal women.
AIMS: In the current study, we explored the potential effects of hormone therapy (HT) on language functioning in healthy, postmenopausal women and compared them with men of similar ages. MATERIALS & METHODS: Language functioning on tasks of verbal fluency and object naming was examined in 100 participants (mean age: 61.9 years; 33 HT users, 15 HT non-users and 52 men) at baseline and follow-up (mean follow-up time period: 2.6 years). RESULTS: At baseline, men had higher composite language scores than HT users. However, HT users demonstrated more improvement over time compared with men, whereas HT non-users performed similarly to men, with no improvement over time. Longer duration of HT use was not associated with improved performance on language tests. CONCLUSION: These results suggest an association between HT use and better language ability in postmenopausal women.
Entities:
Keywords:
cognitive decline; estrogen; hormone therapy; language functioning; postmenopausal women
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