Literature DB >> 25705043

Effect of multipotent stromal cells on the function of cell mitochondria in regenerating liver.

A V El'chaninov1, M A Volodina, I V Arutyunyan, A V Makarov, N V Tarasova, E Yu Kananykhina, N Yu Usman, M V Marei, M Yu Vysokikh, V V Glinkina, G B Bol'shakova, T H Fatkhudinov, G T Sukhikh.   

Abstract

Intrasplenic allogeneic transplantation of multipotent stromal cells from the umbilical cord stimulates hepatocyte proliferation and promotes recovery of liver weight in rats after subtotal resection (80% organ weight). It can be hypothesized that this effect of multipotent stromal cells is due to more rapid recovery of the number of mitochondria and normalization of mitochondrial function of liver hepatocytes.

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Year:  2015        PMID: 25705043     DOI: 10.1007/s10517-015-2808-x

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  2 in total

Review 1.  Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy.

Authors:  Irina Arutyunyan; Andrey Elchaninov; Andrey Makarov; Timur Fatkhudinov
Journal:  Stem Cells Int       Date:  2016-08-29       Impact factor: 5.443

2.  Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model.

Authors:  Jae Yeon Kim; Jong Ho Choi; Ji Hye Jun; Sohae Park; Jieun Jung; Si Hyun Bae; Gi Jin Kim
Journal:  Stem Cell Res Ther       Date:  2020-11-27       Impact factor: 6.832

  2 in total

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