| Literature DB >> 2570416 |
H von der Leyen1, W Schmitz, H Scholz, J Scholz.
Abstract
New knowledge and insight into cardiac muscle physiology and pharmacology together with the development of novel drugs may change the treatment of congestive heart failure in the future. This article reviews two newer inotropic mechanisms currently under investigation. It will place special emphasis on the mechanisms of action of selective cardiac phosphodiesterase inhibition and of alpha 1-adrenoceptor mediated stimulation of the phosphoinositide pathway.Entities:
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Year: 1989 PMID： 2570416 DOI： 10.1016/1043-6618(89)90150-3
Source DB: PubMed Journal: Pharmacol Res ISSN： 1043-6618 Impact factor: 7.658