Literature DB >> 25702655

Bilateral breast radiation delivered with static angle tomotherapy (TomoDirect): clinical feasibility and dosimetric results of a single patient.

Pierfrancesco Franco1, Fernanda Migliaccio, Paolo Torielli, Piera Sciacero, Giuseppe Girelli, Domenico Cante, Cecilia Arrichiello, Valeria Casanova Borca, Andrea Peruzzo Cornetto, Gianmauro Numico, Maria Rosa La Porta, Santi Tofani, Umberto Ricardi.   

Abstract

We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions (2.25 Gy daily) to the bilateral whole breast and 50 Gy/20 fractions (2.5 Gy daily) to the 2 lumpectomy cavities. Treatment was delivered over 4 weeks. Dosimetric results were robust with consistent target coverage and adequate normal tissue avoidance. Treatment was generally well-tolerated and acute toxicity profile was mild. The present report highlights the promising clinical feasibility of TomoDirect for bilateral breast irradiation.

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Year:  2015        PMID: 25702655     DOI: 10.5301/tj.5000264

Source DB:  PubMed          Journal:  Tumori        ISSN: 0300-8916            Impact factor:   2.098


  2 in total

1.  Synchronous bilateral breast cancer irradiation: clinical and dosimetrical issues using volumetric modulated arc therapy and simultaneous integrated boost.

Authors:  Alba Fiorentino; Rosario Mazzola; Stefania Naccarato; Niccolò Giaj-Levra; Sergio Fersino; Gianluisa Sicignano; Umberto Tebano; Francesco Ricchetti; Ruggero Ruggieri; Filippo Alongi
Journal:  Radiol Med       Date:  2017-02-21       Impact factor: 3.469

2.  Comparison of Helical Tomotherapy and Direct Tomotherapy in Bilateral Whole Breast Irradiation in a Case of Bilateral Synchronous Grade 1 and Stage 1 Breast Cancer.

Authors:  Valentina Lancellotta; Martina Iacco; Elisabetta Perrucci; Claudio Zucchetti; Anna Concetta Dipilato; Lorenzo Falcinelli; Isabella Palumbo; Cynthia Aristei
Journal:  Am J Case Rep       Date:  2017-09-22
  2 in total

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