| Literature DB >> 25702655 |
Pierfrancesco Franco1, Fernanda Migliaccio, Paolo Torielli, Piera Sciacero, Giuseppe Girelli, Domenico Cante, Cecilia Arrichiello, Valeria Casanova Borca, Andrea Peruzzo Cornetto, Gianmauro Numico, Maria Rosa La Porta, Santi Tofani, Umberto Ricardi.
Abstract
We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions (2.25 Gy daily) to the bilateral whole breast and 50 Gy/20 fractions (2.5 Gy daily) to the 2 lumpectomy cavities. Treatment was delivered over 4 weeks. Dosimetric results were robust with consistent target coverage and adequate normal tissue avoidance. Treatment was generally well-tolerated and acute toxicity profile was mild. The present report highlights the promising clinical feasibility of TomoDirect for bilateral breast irradiation.Entities:
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Year: 2015 PMID: 25702655 DOI: 10.5301/tj.5000264
Source DB: PubMed Journal: Tumori ISSN: 0300-8916 Impact factor: 2.098