Literature DB >> 25702524

Clonal and horizontal spread of the blaOXA-232 gene among Enterobacteriaceae in a Korean hospital.

Seok Hoon Jeong1, Kyu Man Lee2, Jacob Lee3, Il Kwon Bae4, Jae-Seok Kim2, Han-Sung Kim2, Wonkeun Song5.   

Abstract

All 16 Klebsiella pneumoniae isolates and both Escherichia coli isolates harbored the bla(OXA-232) and bla(CTX-M-15) genes. Furthermore, all 16 K. pneumoniae isolates belonged to a unique pulsed-field gel electrophoresis clone and were assigned to an identical sequence type (ST14). The 2 E. coli isolates were identified as ST131 and ST457. The bla(OXA-232) gene underwent horizontal transfer to E. coli isolates via a conjugative ColE-type plasmid. The introduction of this K. pneumoniae ST14 strain to the Korean hospital was attributed to an index patient who was likely colonized during a prior hospitalization in India.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  ColE-type plasmid; Klebsiella pneumoniae ST14; OXA-232; OXA-48

Mesh：

Substances：

Year:  2015        PMID： 25702524     DOI： 10.1016/j.diagmicrobio.2015.02.001

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


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