Literature DB >> 25701156

Simplification improves understanding of informed consent information in clinical trials regardless of health literacy level.

Eun Jin Kim1, Su Hyun Kim2.   

Abstract

BACKGROUND: This study evaluated the effect of a simplified informed consent form for clinical trials on the understanding and efficacy of informed consent information across health literacy levels.
METHODS: A total of 150 participants were randomly assigned to one of two groups and provided with either standard or simplified consent forms for a cancer clinical trial. The features of the simplified informed consent form included plain language, short sentences, diagrams, pictures, and bullet points.
RESULTS: Levels of objective and subjective understanding were significantly higher in participants provided with simplified informed consent forms relative to those provided with standard informed consent forms. The interaction effects between type of consent form and health literacy level on objective and subjective understanding were nonsignificant.
CONCLUSION: Simplified informed consent was effective in enhancing participant's subjective and objective understanding regardless of health literacy.
© The Author(s) 2015.

Entities:  

Keywords:  Informed consent; clinical trial; health literacy

Mesh:

Year:  2015        PMID: 25701156     DOI: 10.1177/1740774515571139

Source DB:  PubMed          Journal:  Clin Trials        ISSN: 1740-7745            Impact factor:   2.486


  19 in total

1.  Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability.

Authors:  Lauren A McCormack; Amanda Wylie; Rebecca Moultrie; Robert D Furberg; Anne C Wheeler; Katherine Treiman; Donald B Bailey; Melissa Raspa
Journal:  PLoS One       Date:  2019-10-23       Impact factor: 3.240

Review 2.  Informed Consent to Research with Cognitively Impaired Adults: Transdisciplinary Challenges and Opportunities.

Authors:  Beth Prusaczyk; Steven M Cherney; Christopher R Carpenter; James M DuBois
Journal:  Clin Gerontol       Date:  2016-06-20       Impact factor: 2.619

3.  Understanding the Use of Optimal Formatting and Plain Language When Presenting Key Information in Clinical Trials.

Authors:  Erin D Solomon; Jessica Mozersky; Matthew P Wroblewski; Kari Baldwin; Meredith V Parsons; Melody Goodman; James M DuBois
Journal:  J Empir Res Hum Res Ethics       Date:  2021-08-19       Impact factor: 1.742

Review 4.  Towards a more patient-centered clinical trial process: A systematic review of interventions incorporating health literacy best practices.

Authors:  Mehnaz Bader; Linda Zheng; Deepika Rao; Olayinka Shiyanbola; Laurie Myers; Terry Davis; Catina O'Leary; Michael McKee; Michael Wolf; Annlouise R Assaf
Journal:  Contemp Clin Trials       Date:  2022-03-15       Impact factor: 2.261

5.  The "Ought-Is" Problem: An Implementation Science Framework for Translating Ethical Norms Into Practice.

Authors:  Bryan A Sisk; Jessica Mozersky; Alison L Antes; James M DuBois
Journal:  Am J Bioeth       Date:  2020-05       Impact factor: 11.229

6.  Too Dense and Too Detailed: Evaluation of the Health Literacy Attributes of an Informed Consent Document.

Authors:  Vanessa W Simonds; Dedra Buchwald
Journal:  J Racial Ethn Health Disparities       Date:  2019-12-10

7.  Translating medical documents improves students' communication skills in simulated physician-patient encounters.

Authors:  Anja Bittner; Johannes Bittner; Ansgar Jonietz; Christoph Dybowski; Sigrid Harendza
Journal:  BMC Med Educ       Date:  2016-02-27       Impact factor: 2.463

8.  The marketing plan and outcome indicators for recruiting and retaining parents in the HomeStyles randomized controlled trial.

Authors:  Carol Byrd-Bredbenner; Colleen Delaney; Jennifer Martin-Biggers; Mallory Koenings; Virginia Quick
Journal:  Trials       Date:  2017-11-15       Impact factor: 2.279

9.  The effects of presenting oncologic information in terms of opposites in a medical context.

Authors:  Roberto Burro; Ugo Savardi; Maria Antonietta Annunziata; Paolo De Paoli; Ivana Bianchi
Journal:  Patient Prefer Adherence       Date:  2018-03-27       Impact factor: 2.711

10.  Patient representatives' views on patient information in clinical cancer trials.

Authors:  Pia Dellson; Mef Nilbert; Christina Carlsson
Journal:  BMC Health Serv Res       Date:  2016-02-01       Impact factor: 2.655

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