Literature DB >> 2570

Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation.

J C Hyde, N Robinson.   

Abstract

A method for the chemical fixation of the enzyme GABA-transaminase in nervous tissue is described. It is shown that after perfusion with a formaldehyde/glutaraldehyde fixative, activity of the enzyme in cerebellar cortex is demonstrable whilst cellular morphology is preserved. Results from the improved technique have shown new sites of GABA-transaminase activity in cerebellar cortex. In view of these results a special function for glial cells in this area of brain has been suggested.

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Year:  1976        PMID: 2570     DOI: 10.1007/BF02462790

Source DB:  PubMed          Journal:  Histochemistry        ISSN: 0301-5564


  27 in total

1.  [Quantitative investigations of the histochemical evidence of GABA-transaminase-SSA-dehydrogenase (author's transl)].

Authors:  J Ritter
Journal:  Acta Histochem       Date:  1973       Impact factor: 2.479

2.  Autoradiographic localization of 3 H-GABA in rat retina.

Authors:  M J Neal; L L Iversen
Journal:  Nat New Biol       Date:  1972-02-16

3.  Pharmacological properties of the postsynaptic inhibition by Purkinje cell axons and the action of gamma-aminobutyric acid on deiters NEURONES.

Authors:  K Obata; M Ito; R Ochi; N Sato
Journal:  Exp Brain Res       Date:  1967       Impact factor: 1.972

4.  Histochemical localization of brain succinic semialdehyde dehydrogenase--a -aminobutyric acid degradative enzyme.

Authors:  K L Sims; H A Weitsen; F E Bloom
Journal:  J Histochem Cytochem       Date:  1971-07       Impact factor: 2.479

5.  Intracellular localization of glutamate decarboxylase, gamma-aminobutyrate transaminase and some other enzymes in brain tissue.

Authors:  G M van Kempen; C J van den Berg; H J van der Helm; H Veldstra
Journal:  J Neurochem       Date:  1965-07       Impact factor: 5.372

6.  Localisation of sites of GABA catabolism in the rat retina.

Authors:  J C Hyde; N Robinson
Journal:  Nature       Date:  1974-03-29       Impact factor: 49.962

7.  Patterns of cytochemical staining in Golgi apparatus of amebae following enucleation.

Authors:  G E Wise; C J Flickinger
Journal:  Exp Cell Res       Date:  1971-08       Impact factor: 3.905

8.  Electron microscopic cytochemical study of glutamic oxalacetic transaminase activity in ischemic myocardium.

Authors:  S H Lee; J Dusek; G Rona
Journal:  J Mol Cell Cardiol       Date:  1971-09       Impact factor: 5.000

9.  Cellular localization of labeled gamma-aminobutyric acid (3H-GABA) in rat cerebellar cortex: an autoradiographic study.

Authors:  T Hökfelt; A Ljungdahl
Journal:  Brain Res       Date:  1970-09-16       Impact factor: 3.252

10.  Appearance of gamma aminobutyrate transaminase activity in developing rat brain.

Authors:  J C Hyde; N Robinson
Journal:  J Neurochem       Date:  1974-08       Impact factor: 5.372

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  6 in total

1.  Late postnatal changes in rat somatosensory cortex. Temporal and spatial relationships of GABA-T and AChE histochemical reactivity.

Authors:  D A Kristt; J V Waldman
Journal:  Anat Embryol (Berl)       Date:  1986

Review 2.  In situ measurements of enzyme activities in the brain.

Authors:  P Kugler
Journal:  Histochem J       Date:  1993-05

3.  Ultrastructural demonstration of glucose 6-phosphatase in cerebral cortex.

Authors:  S Y Al-Ali; N Robinson
Journal:  Histochemistry       Date:  1981

4.  Microphotometric determination of enzymes in brain sections. II. GABA transaminase.

Authors:  P Kugler; G Baier
Journal:  Histochemistry       Date:  1990

5.  Electron cytochemical localization of gamma-aminobutyric acid catabolism in rat cerebellar cortex.

Authors:  J C Hyde; N Robinson
Journal:  Histochemistry       Date:  1976-10-07

6.  Neuronal and glial localization of acetylcholinesterase and GABA transaminase in organized cultures of developing rat spinal cord.

Authors:  L W Haynes
Journal:  Experientia       Date:  1983-02-15
  6 in total

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