Literature DB >> 25699705

Micro(RNA) managing by mTORC1.

Jenna L Jewell1, Fabian Flores1, Kun-Liang Guan2.   

Abstract

In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25699705      PMCID： PMC4378617          DOI： 10.1016/j.molcel.2015.02.006

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  9 in total

Review 1.  Regulation of microRNA biogenesis.

Authors:  Minju Ha; V Narry Kim
Journal:  Nat Rev Mol Cell Biol       Date:  2014-07-16       Impact factor: 94.444

Review 2.  MicroRNAs in stress signaling and human disease.

Authors:  Joshua T Mendell; Eric N Olson
Journal:  Cell       Date:  2012-03-16       Impact factor: 41.582

3.  An mTORC1-Mdm2-Drosha axis for miRNA biogenesis in response to glucose- and amino acid-deprivation.

Authors:  Peiying Ye; Yu Liu; Chong Chen; Fei Tang; Qi Wu; Xiang Wang; Chang-Gong Liu; Xiuping Liu; Runhua Liu; Yang Liu; Pan Zheng
Journal:  Mol Cell       Date:  2015-01-29       Impact factor: 17.970

4.  Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring.

Authors:  Emilyn U Alejandro; Brigid Gregg; Taylor Wallen; Doga Kumusoglu; Daniel Meister; Angela Chen; Matthew J Merrins; Leslie S Satin; Ming Liu; Peter Arvan; Ernesto Bernal-Mizrachi
Journal:  J Clin Invest       Date:  2014-09-02       Impact factor: 14.808

Review 5.  mTOR: from growth signal integration to cancer, diabetes and ageing.

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6.  Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis.

Authors:  Yuting Sun; Yejing Ge; Jenny Drnevich; Yong Zhao; Mark Band; Jie Chen
Journal:  J Cell Biol       Date:  2010-06-21       Impact factor: 10.539

7.  Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

Authors:  Chung-Han Lee; Ken Inoki; Magdalena Karbowniczek; Emmanuel Petroulakis; Nahum Sonenberg; Elizabeth Petri Henske; Kun-Liang Guan
Journal:  EMBO J       Date:  2007-10-25       Impact factor: 11.598

Review 8.  Amino acid signalling upstream of mTOR.

Authors:  Jenna L Jewell; Ryan C Russell; Kun-Liang Guan
Journal:  Nat Rev Mol Cell Biol       Date:  2013-01-30       Impact factor: 94.444

9.  Reprogramming of the microRNA transcriptome mediates resistance to rapamycin.

Authors:  Hana Totary-Jain; Despina Sanoudou; Iddo Z Ben-Dov; Cula N Dautriche; Paolo Guarnieri; Steven O Marx; Thomas Tuschl; Andrew R Marks
Journal:  J Biol Chem       Date:  2013-01-08       Impact factor: 5.157
  9 in total
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Review 3.  The Sensitivity Prediction of Neoadjuvant Chemotherapy for Gastric Cancer.

Authors:  Juan Sun; Xianze Wang; Zimu Zhang; Ziyang Zeng; Siwen Ouyang; Weiming Kang
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  3 in total

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