| Literature DB >> 25698847 |
Vindya S Perera1, Haijian Liu1, Zhi-Qiang Wang1, Songping D Huang1.
Abstract
A layer-by-layer self-assembly method leads to the formation of Au@ZnMoS4 core-shell nanoparticles (NPs). The PEGylated Au@ZnMoS4 NPs are highly water-dispersible, exhibit no cytotoxicity and can penetrate the cell membrane to selectively remove copper(I) ions from HepG2 cells in the presence of other endogenous and biologically essential metal ions including Mg(II), Ca(II), Mn(II) and Fe(II), demonstrating their potential as a novel intracellular copper detoxifying agent.Entities:
Keywords: Biomedical Applications; Core/Shell Nanoparticles; Drug Delivery; Functional Coatings; Gold Nanoparticles; Layer-by-Layer Self-Assembly
Year: 2013 PMID: 25698847 PMCID: PMC4331036 DOI: 10.1021/cm402147u
Source DB: PubMed Journal: Chem Mater ISSN: 0897-4756 Impact factor: 9.811