Literature DB >> 25698219

In vitro anti-oxidant potential of new metabolites from Hypericum oblongifolium (Guttiferae).

Naila Raziq1,2, Muhammad Saeed1, Muhammad Shaiq Ali3, Salman Zafar4, Muhammad Imran Ali3,5.   

Abstract

Phytochemical investigations on Hypericum oblongifolium led to the isolation of a flavone named folicitin (1) and a bicyclic conjugated lactone, folenolide (2) from the ethyl acetate fraction of methanolic extract. Both metabolites were characterised as new compounds based on detailed spectroscopic analyses. In vitro anti-oxidant potential of both the compounds was evaluated by the DPPH radical scavenging assay. Compound 1 exhibited significant antioxidant activity while compound 2 was found inactive.

Entities:  

Keywords:  Guttiferae; Hypericum oblongifolium; antioxidant; flavone; folenolide; folicitin

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Year:  2015        PMID: 25698219     DOI: 10.1080/14786419.2015.1009064

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  2 in total

1.  Folecitin Isolated from Hypericum oblongifolium Exerts Neuroprotection against Lipopolysaccharide-Induced Neuronal Synapse and Memory Dysfunction via p-AKT/Nrf-2/HO-1 Signalling Pathway.

Authors:  Umar Farooq; Muhammad Umar Khayam Sahibzada; Taous Khan; Rahim Ullah; Muhammad Shahid; Ameer Khusro; Veronique Seidel; Magda H Abdellattif; Talha Bin Emran
Journal:  Evid Based Complement Alternat Med       Date:  2022-03-28       Impact factor: 2.629

2.  Pharmacological basis for the use of Hypericum oblongifolium as a medicinal plant in the management of pain, inflammation and pyrexia.

Authors:  Naila Raziq; Muhammad Saeed; Muhammad Shahid; Naveed Muhammad; Haroon Khan; Farah Gul
Journal:  BMC Complement Altern Med       Date:  2016-02-01       Impact factor: 3.659

  2 in total

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