BACKGROUND: Percutaneous transluminal septal myocardial ablation (PTSMA) is a new interventional technique to treat patients with hypertrophic cardiomyopathy. METHODS: Small doses of ethanol 96% were injected into a targeted septal artery causing a chemical myocardial infarction. Three patients were evaluated, including a follow-up of three months. RESULTS: There were no complications during the procedure LVOT gradient was reduced from 120±140 mmHg. At follow-up, all three patients showed improvement in validity. CONCLUSION: The method requires an echocardiographic contrast determination of the myocardium at risk for ethanol treatment, in addition to haemodynamic monitoring.
BACKGROUND: Percutaneous transluminal septal myocardial ablation (PTSMA) is a new interventional technique to treat patients with hypertrophic cardiomyopathy. METHODS: Small doses of ethanol 96% were injected into a targeted septal artery causing a chemical myocardial infarction. Three patients were evaluated, including a follow-up of three months. RESULTS: There were no complications during the procedure LVOT gradient was reduced from 120±140 mmHg. At follow-up, all three patients showed improvement in validity. CONCLUSION: The method requires an echocardiographic contrast determination of the myocardium at risk for ethanol treatment, in addition to haemodynamic monitoring.
Authors: F H Gietzen; C J Leuner; U Raute-Kreinsen; A Dellmann; J Hegselmann; C Strunk-Mueller; H J Kuhn Journal: Eur Heart J Date: 1999-09 Impact factor: 29.983
Authors: N M Lakkis; S F Nagueh; N S Kleiman; D Killip; Z X He; M S Verani; R Roberts; W H Spencer Journal: Circulation Date: 1998-10-27 Impact factor: 29.690